Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Preprint |
| Published: |
2024
|
| Subjects: | |
| Online Access: | https://arxiv.org/abs/2401.08321 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1866917577341534208 |
|---|---|
| author | Wątorek, Marcin Tomczyk, Wojciech Gawłowska, Magda Golonka-Afek, Natalia Żyrkowska, Aleksandra Marona, Monika Wnuk, Marcin Słowik, Agnieszka Ochab, Jeremi K. Fafrowicz, Magdalena Marek, Tadeusz Oświęcimka, Paweł |
| author_facet | Wątorek, Marcin Tomczyk, Wojciech Gawłowska, Magda Golonka-Afek, Natalia Żyrkowska, Aleksandra Marona, Monika Wnuk, Marcin Słowik, Agnieszka Ochab, Jeremi K. Fafrowicz, Magdalena Marek, Tadeusz Oświęcimka, Paweł |
| contents | Quantifying the complex/multifractal organization of the brain signals is crucial to fully understanding the brain processes and structure. In this contribution, we performed the multifractal analysis of the electroencephalographic (EEG) data obtained from a controlled multiple sclerosis (MS) study, focusing on the correlation between the degree of multifractality, disease duration, and disability level. Our results reveal a significant correspondence between the complexity of the time series and multiple sclerosis development, quantified respectively by scaling exponents and the Expanded Disability Status Scale (EDSS). Namely, for some brain regions, a well-developed multifractality and little persistence of the time series were identified in patients with a high level of disability, whereas the control group and patients with low EDSS were characterised by persistence and monofractality of the signals. The analysis of the cross-correlations between EEG signals supported these results, with the most significant differences identified for patients with EDSS $> 1$ and the combined group of patients with EDSS $\leq 1$ and controls. No association between the multifractality and disease duration was observed, indicating that the multifractal organisation of the data is a hallmark of developing the disease. The observed complexity/multifractality of EEG signals is hypothetically a result of neuronal compensation -- i.e., of optimizing neural processes in the presence of structural brain degeneration. The presented study is highly relevant due to the multifractal formalism used to quantify complexity and due to scarce resting-state EEG evidence for cortical reorganization associated with compensation. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2401_08321 |
| institution | arXiv |
| publishDate | 2024 |
| record_format | arxiv |
| spellingShingle | Multifractal organization of EEG signals in Multiple Sclerosis Wątorek, Marcin Tomczyk, Wojciech Gawłowska, Magda Golonka-Afek, Natalia Żyrkowska, Aleksandra Marona, Monika Wnuk, Marcin Słowik, Agnieszka Ochab, Jeremi K. Fafrowicz, Magdalena Marek, Tadeusz Oświęcimka, Paweł Neurons and Cognition Disordered Systems and Neural Networks Adaptation and Self-Organizing Systems Quantitative Methods Quantifying the complex/multifractal organization of the brain signals is crucial to fully understanding the brain processes and structure. In this contribution, we performed the multifractal analysis of the electroencephalographic (EEG) data obtained from a controlled multiple sclerosis (MS) study, focusing on the correlation between the degree of multifractality, disease duration, and disability level. Our results reveal a significant correspondence between the complexity of the time series and multiple sclerosis development, quantified respectively by scaling exponents and the Expanded Disability Status Scale (EDSS). Namely, for some brain regions, a well-developed multifractality and little persistence of the time series were identified in patients with a high level of disability, whereas the control group and patients with low EDSS were characterised by persistence and monofractality of the signals. The analysis of the cross-correlations between EEG signals supported these results, with the most significant differences identified for patients with EDSS $> 1$ and the combined group of patients with EDSS $\leq 1$ and controls. No association between the multifractality and disease duration was observed, indicating that the multifractal organisation of the data is a hallmark of developing the disease. The observed complexity/multifractality of EEG signals is hypothetically a result of neuronal compensation -- i.e., of optimizing neural processes in the presence of structural brain degeneration. The presented study is highly relevant due to the multifractal formalism used to quantify complexity and due to scarce resting-state EEG evidence for cortical reorganization associated with compensation. |
| title | Multifractal organization of EEG signals in Multiple Sclerosis |
| topic | Neurons and Cognition Disordered Systems and Neural Networks Adaptation and Self-Organizing Systems Quantitative Methods |
| url | https://arxiv.org/abs/2401.08321 |