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| Main Author: | |
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| Format: | Recurso digital |
| Language: | English |
| Published: |
Zenodo
2023
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| Subjects: | |
| Online Access: | https://doi.org/10.5281/zenodo.10312833 |
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Table of Contents:
- <p>Recent studies have shown that electronic cigarettes (or e-cigarettes) may produce high levels of aldehydes, especially from using flavored e-liquids, but results are presented with high variation. The goal of this study was to evaluate the impact of flavoring and e-liquid composition on the level of aldehydes in the aerosol produced from 3<sup>rd</sup>-gen Vaporesso and 4<sup>th</sup>-gen JUUL e-cigarettes using an in-house apparatus. Aerosol samples were collected via 2,4-dinitrophenylhydrazine cartridges and analyzed with high performance liquid chromatography. Results for Vaporesso showed the formaldehyde concentrations to be 0.563 ± 0.177 µg/puff, 0.730 ± 0.181 µg/puff, and 0.612 ± 0.096 µg/puff for unflavored, vanillin flavored, and acetovanillone flavored samples, respectively. There were no statistically significant differences between the mean formaldehyde concentrations in flavored e-liquids compared to unflavored e-liquid. In addition, traces of unreacted flavorings were detected in the chromatograms of aerosol samples. These results indicated that flavoring chemicals specifically might not contribute to the aldehyde concentration measured under normal puffing condition. Results for JUUL showed that Virginia Tobacco pods produced a formaldehyde concentration of 0.060 ± 0.030 µg/puff, whereas it was 0.014 ± 0.013 µg/puff for Menthol pods. This shows that Virginia Tobacco pods produce six times more formaldehyde than Menthol pods, a statistically significant difference, indicating that the choice of pod flavor impacts the concentration of formaldehyde. The concentration of nicotine did not have a significant influence on formaldehyde production for these two flavors. Combined results from Vaporesso and JUUL demonstrated the need to further explore other constituents in the e-liquid that might contribute to the aldehyde levels found in 3<sup>rd</sup>-gen Vaporesso and 4<sup>th</sup>-gen e-cigarette devices.</p>