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| Main Authors: | , , , , , , , |
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| Formato: | Recurso digital |
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Zenodo
2021
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| Acesso em linha: | https://doi.org/10.5281/zenodo.13466534 |
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Sumário:
- (Uploaded by Plazi for the Bat Literature Project) Thirty-five Escherichia coli isolates obtained from the liver, spleen and intestines of 180 frugivorous and insec tivorous bats were investigated for antimicrobial resistance phenotypes/genotypes, prevalence of ExtendedSpectrum beta-lactamase (ESBL) production, virulence gene detection and molecular typing. Eight (22.9 %) of the isolates were multidrug resistant (MDR). Two isolates were cefotaxime-resistant, ESBL-producers and harbored the blaCTX-M-15 gene; they belonged to ST10184-D and ST2178-B1 lineages. tet(A) gene was detected in all tetracycline-resistant isolates while int1 (n = 8) and blaTEM (n = 7) genes were also found. Thirty-three of the E. coli isolates were assigned to seven phylogenetic groups, with B1 (45.7 %) being predominant. Three isolates were enteropathogenic E. coli (EPEC) pathovars, containing the eae gene (with the variants gamma and iota), and lacking stx1/stx2 genes. Bats in Nigeria are possible reservoirs of potentially pathogenic MDR E. coli isolates which may be important in the ecology of antimicrobial resistance at the human-livestock-wildlife-environment interfaces. The study reinforces the importance of including wildlife in national antimicrobial resistance moni toring programmes.