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| Hovedforfatter: | |
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| Format: | Recurso digital |
| Sprog: | engelsk |
| Udgivet: |
Zenodo
2025
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| Fag: | |
| Online adgang: | https://doi.org/10.5281/zenodo.15124689 |
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Indholdsfortegnelse:
- <p>Abstract:<br>Introduction: Neonatal seizures represent the most prevalent neurological disorder in newborns <br>and are critical for neurodevelopmental outcomes [1]. These seizures frequently occur during <br>the neonatal period, with an incidence ranging from 1.5 to 5.5 per 1000 live births, and are <br>more prevalent in preterm infants due to brain immaturity and increased risk of injury [2,3]. <br>They signify neurological dysfunction, which may be reversible or persistent depending on <br>the underlying cause. Prompt diagnosis and intervention are imperative to reduce mortality and <br>mitigate long-term neurological consequences.Methods: This prospective cohort study was conducted on neonates admitted with seizures between January 2022 and March 2023 in the Neonatology Division, Department of <br>Pediatrics, GMC Srinagar. Following history taking, physical examination, and etiological screening, data were systematically recorded. Neonates were monitored in a high-risk neonatal outpatient department, conducted biweekly. The Amiel Tison neurological examination was performed at discharge and during follow-up. Neurodevelopmental assessment was conducted at 6 and 12 months using the Denver Developmental Screening Test II (DDST – II) <br>in collaboration with a clinical psychologist. Univariate analysis was employed to examine <br>the relationship between risk factors and neurodevelopmental outcomes. Categorical data <br>were compared using the Chi-square or Fisher’s exact test, with statistical significance set at p ≤ <br>0.05. Relative Risk (RR) with a 95% confidence interval (CI) was calculated.Results: During the study period, 367 neonates <br>were admitted to the NICU with seizures. After applying the selection criteria, 120 neonates <br>were included in the study. It was observed that 61.66% (n=74) exhibited normal development, </p>