Shranjeno v:
| Glavni avtor: | |
|---|---|
| Format: | Recurso digital |
| Jezik: | angleščina |
| Izdano: |
Zenodo
2025
|
| Teme: | |
| Online dostop: | https://doi.org/10.5281/zenodo.15849157 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|
Kazalo:
- <p><span>This study examined the creation and assessment of mobile health (mHealth) applications aimed at facilitating opioid addiction recovery in California, emphasizing evidence-based interventions.<span> </span>A total of 196 people with opioid use disorder (OUD) were enrolled and randomized into intervention (n = 98) and control (n = 98) groups, with stratified randomization being used to confirm balanced baseline characteristics.<span> </span>Over 24 weeks, the intervention group, which used a specialized mHealth application, demonstrated considerably higher decreases in opioid usage than the control group.<span> </span>The number of days of opioid use decreased from 8.9 to 2.7 in the intervention group, compared to a reduction from 9.1 to 5.8 in the control group (IRR = 0.46, 95% CI = 0.30–0.70, p < .001).<span> </span>Treatment retention was significantly greater among app users, with 83% continuing on MOUD at week 24, in contrast to 66% in the control group (OR = 2.67, 95% CI = 1.37–5.19, p = .004).<span> </span>Increased application involvement is associated with significantly enhanced retention advantages (OR = 3.55, 95% CI = 1.63–7.72).<span> </span>Secondary outcomes indicated enhanced mental health, evidenced by more significant reductions in PHQ-9 and GAD-7 scores among application users, as well as increased EQ-5D quality-of-life improvements (p = .016). Three engagement trajectories were identified by latent growth modeling, with "high-stable" users attaining the most advantageous outcomes.<span> </span>Thematic analysis of 37 interviews corroborated these findings, emphasizing the motivational impact of real-time feedback, the cultural significance of multilingual communication, privacy safeguards, and the necessity of connectivity for rural participants.<span> </span>The findings indicate that customized, interactive mHealth applications can improve OUD treatment outcomes and mitigate structural obstacles to recovery among various communities in California.</span></p>