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| Hlavní autor: | |
|---|---|
| Médium: | Recurso digital |
| Jazyk: | angličtina |
| Vydáno: |
Zenodo
2025
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| On-line přístup: | https://doi.org/10.5281/zenodo.17878519 |
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Obsah:
- <p><em><span lang="EN-IN">Sukha Prasava Nabhi Lepa,</span></em><span lang="EN-IN"> a classical formulation described in the <em>Stri Garbha Rogadhikara</em> of<em> Yogaratnakara</em>. </span><span lang="EN-IN">Transforming the traditional <em>Lepa</em> into a transdermal patch allows its administration through the navel region, providing a simple, non-invasive, and patient-comfortable mode of delivery.</span><span lang="EN-IN"> </span><span lang="EN-IN">Transdermal systems are known for their convenient application, controlled drug release, and affordability, all of which may improve patient compliance and treatment results. </span><span lang="EN-IN">This study includes analytical study of <em>Sukhaprasava nabhi lepa</em> and invitro diffusion study of Topical patch. The analytical study was carried out to standardize Sukhaprasava Nabhilepa and its modified topical patch formulation through detailed physicochemical and instrumental evaluations. The parameters for Sukhaprasava Nabhilepa included Loss on Drying, Total Ash, Acid Insoluble, TLC, HPTLC etc. The topical patch was evaluated for Folding Endurance, Tensile Strength, Thickness, and Percentage Elongation at Break, Percentage Moisture Content, pH, and Percentage Moisture Uptake etc. </span><span lang="EN-IN">The analytical parameters collectively provide a comprehensive profile for both formulations, ensuring quality assurance and reproducibility while supporting their potential pharmaceutical applicability.</span></p>