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| Formatua: | Recurso digital |
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Zenodo
2026
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| Gaiak: | |
| Sarrera elektronikoa: | https://doi.org/10.5281/zenodo.18207521 |
| Etiketak: |
Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!
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| _version_ | 1866901220264771584 |
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| author | Nandita Tangale*, Dr. Preeti Sable, Dr. Shushama Vaishnav, Dr. Praveen Wakte |
| author_facet | Nandita Tangale*, Dr. Preeti Sable, Dr. Shushama Vaishnav, Dr. Praveen Wakte |
| contents | <p><span>Melittin, the main bioactive component of honey bee venom (HBV), demonstrates significant therapeutic promise, especially as an anticancer agent. This review explores the physicochemical and pharmacological properties of HBV, highlighting melittin's mechanisms of action against cancer cells, such as triggering apoptosis, inhibiting cell proliferation, and preventing metastasis. The effects of traditional collection methods and advanced extraction technologies, including electric shock devices, on venom composition are examined. The study delved deeper into advanced analytical methods such as SDS-PAGE, HPLC-MS, and LC-MS, which are vital to the separation and identification of melittin from venom of honey bees. This study examines these approaches I greater detail. It also looks at delivery systems mediated by nanotechnology as an innovative approach to maximize melittin's therapeutic effectiveness while lowering systemic toxicity. This review highlights melittin's potential as a cancer treatment choice in the future and encourages ongoing advancements in analytical and delivery systems to promote pharmacotherapies based on HBV.</span></p> |
| format | Recurso digital |
| id | zenodo_https___doi_org_10_5281_zenodo_18207521 |
| institution | Zenodo |
| language | |
| publishDate | 2026 |
| publisher | Zenodo |
| record_format | zenodo |
| spellingShingle | Characterization of Melittin from Honey Bee Venom using Analytical Methods Nandita Tangale*, Dr. Preeti Sable, Dr. Shushama Vaishnav, Dr. Praveen Wakte Melittin, Honey bee venom, SDS-PAGE, HPLC-MS, LC-MS. <p><span>Melittin, the main bioactive component of honey bee venom (HBV), demonstrates significant therapeutic promise, especially as an anticancer agent. This review explores the physicochemical and pharmacological properties of HBV, highlighting melittin's mechanisms of action against cancer cells, such as triggering apoptosis, inhibiting cell proliferation, and preventing metastasis. The effects of traditional collection methods and advanced extraction technologies, including electric shock devices, on venom composition are examined. The study delved deeper into advanced analytical methods such as SDS-PAGE, HPLC-MS, and LC-MS, which are vital to the separation and identification of melittin from venom of honey bees. This study examines these approaches I greater detail. It also looks at delivery systems mediated by nanotechnology as an innovative approach to maximize melittin's therapeutic effectiveness while lowering systemic toxicity. This review highlights melittin's potential as a cancer treatment choice in the future and encourages ongoing advancements in analytical and delivery systems to promote pharmacotherapies based on HBV.</span></p> |
| title | Characterization of Melittin from Honey Bee Venom using Analytical Methods |
| topic | Melittin, Honey bee venom, SDS-PAGE, HPLC-MS, LC-MS. |
| url | https://doi.org/10.5281/zenodo.18207521 |