I tiakina i:
| Kaituhi matua: | |
|---|---|
| Hōputu: | Recurso digital |
| Reo: | Ingarihi |
| I whakaputaina: |
Zenodo
2026
|
| Urunga tuihono: | https://doi.org/10.5281/zenodo.19281801 |
| Ngā Tūtohu: |
Tāpirihia he Tūtohu
Kāore He Tūtohu, Me noho koe te mea tuatahi ki te tūtohu i tēnei pūkete!
|
Rārangi ihirangi:
- <p><span lang="EN-IN">The widespread use of digital devices has led to prolonged exposure to blue light, which is increasingly recognized as a contributing factor <span>in</span> skin damage. Blue light penetrates the skin and induces oxidative stress, leading to premature aging, hyperpigmentation, inflammation, and <span>skin barrier impairment</span>. Conventional topical formulations provide limited protection against blue light–induced damage <span>owing</span> to <span>the </span>poor stability and insufficient skin penetration of active compounds. <span>This study aimed</span> to develop a smart nanoparticle-based topical formulation to enhance protection against blue light–induced skin damage. Nanoparticles are prepared using a suitable technique and loaded with <span>antioxidants</span> and <span>photoprotective</span> agents. The prepared nanoparticles <span>were characterized in terms of</span> particle size, polydispersity index, zeta potential, morphology, and encapsulation efficiency. The optimized nanoparticles <span>were</span> incorporated into a topical dosage form, such as a gel or cream, and evaluated for physicochemical properties, stability, spreadability, and in vitro release behavior. The expected results include improved stability of <span>the </span>active ingredients, enhanced skin penetration, and superior protection against blue light–induced oxidative stress compared to conventional formulations. The nanoparticle-based system is anticipated to exhibit significant antioxidant activity and effective <span>blue-light</span> attenuation, thereby reducing cellular damage. In conclusion, the proposed smart nanoparticle-based topical formulation represents a novel, effective, and safe approach for protecting the skin from blue light–induced damage, offering a promising strategy for next-generation dermocosmetic and therapeutic applications.</span></p>