Sábháilte in:
| Príomhchruthaitheoirí: | , |
|---|---|
| Formáid: | Recurso digital |
| Teanga: | Béarla |
| Foilsithe / Cruthaithe: |
Zenodo
2026
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| Ábhair: | |
| Rochtain ar líne: | https://doi.org/10.5281/zenodo.20302972 |
| Clibeanna: |
Cuir clib leis
Níl clibeanna ann, Bí ar an gcéad duine le clib a chur leis an taifead seo!
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Clár na nÁbhar:
- <p>Tridax procumbens (Linn.), a member of the Asteraceae family, is an indispensable medicinal herb frequently utilized in traditional systems of medicine across Africa and Southeast Asia for wound healing, antiseptic treatment, and pain relief. As pathogenic bacteria increasingly evolve resistance to synthetic medications, there is a critical regulatory and scientific need to explore bioactive compounds from natural sources. This research presents a comprehensive evaluation of the pharmacological biopotentials of T. procumbens leaf extracts, alongside the development of an eco-friendly mosquito repellent formulation. Dried leaf powders were subjected to extraction using aqueous and dimethyl sulphoxide (DMSO) solvents. The anticoagulant activity was analyzed using human blood samples, where the DMSO extract demonstrated remarkable inhibitory effects on clotting time compared to the control group, which clotted in 9 minutes and 24 seconds. Antioxidant potential was assessed through the 1,1-diphenyl-2-picrylhydrazyl (DPPH) scavenging assay. The DMSO extract exhibited a strong dose-dependent scavenging effect with a calculated IC50 value of 2.65 mg/mL, highlighting its significant ability to clear free radicals. Antimicrobial efficacy was tested via the well diffusion method against five bacterial strains. Bacillus spp displayed high sensitivity to the DMSO extract with an 18mm zone of inhibition, whereas other pathogens demonstrated higher resistance levels at the tested concentrations.<br>A primary focus of this study was anti-insecticidal activity, where larvicidal mortality was calculated using probit analysis over a multi-day observation period. The DMSO extract showed a high mortality rate with an LC50 of 15.34 mg/mL. Utilizing these results, a sustainable mosquito repellent candle was formulated using a blend of wax, starch, sandal powder, and eucalyptus oil. Performance evaluations confirmed "Good" repellent activity, moderate smoke visibility, and a consistent burn time of one hour without causing respiratory irritation or offensive odors. These results validate Tridax procumbens as a potent bio-resource for developing non-toxic, commercially viable insect repellents and multi-functional therapeutic agents.</p>