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| Format: | Recurso digital |
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Zenodo
2026
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| Online Access: | https://doi.org/10.5281/zenodo.20375233 |
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Table of Contents:
- <h1>Alvis v1.0.0 - Released on May 25, 2026</h1> <p>First public release of Alvis — a web tool for visualizing amino acid conservation across protein sequence alignments with secondary structure annotation.</p> <h2>Features</h2> <ul> <li>Upload multiple FASTA alignments (individually or as a ZIP) and visualize conserved residues side by side</li> <li>Configurable conservation thresholds per alignment group</li> <li>Optional PDB structure annotation with secondary structure elements (helices, sheets, coils) via DSSP</li> <li>Cross-conservation analysis: identify and visualize positions conserved across protein families</li> <li>Automatic representative sequence selection via PDB chain matching</li> <li>Deployable locally via Docker (docker compose up) or as a standalone Flask app</li> <li>Includes example dataset (globin family)</li> </ul> <h2>Links</h2> <ul> <li>Live instance: https://alvis.idameitil.dk</li> <li>Documentation: see the https://alvis.idameitil.dk/about and README</li> </ul>