שמור ב:
| מחבר ראשי: | |
|---|---|
| פורמט: | Recurso digital |
| שפה: | |
| יצא לאור: |
Zenodo
2026
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| גישה מקוונת: | https://doi.org/10.5281/zenodo.20406029 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
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תוכן הענינים:
- <p>Revised manuscript submission to npj Systems Biology and Applications (May 2026).</p> <p>This release implements Eq. (1)–(6) of the v7.7 manuscript exactly, including:</p> <ul> <li>Hill cross-axis switches (n_axis = 3, K_hill = 0.40)</li> <li>Basal production terms T0, R0, M0</li> <li>Tolerance self-amplification nuT<em>H_up(T)</em>R*(1-T)</li> <li>Bounded (1-D), (1-S) cross-axis terms ensuring DI ∈ [0,1]</li> </ul> <p>Verified to reproduce:</p> <ul> <li>Healthy attractor (T=0.99, D=0.001, S=0.06, E=0.98, R=0.95, M=1.00)</li> <li>Disease attractor (T=0.47, D=0.71, S=0.31, E=0.43, R=0.64, M=0.33)</li> <li>Top-3 sensitivity parameters: beta2, gamma2, beta2e (all in Axis 2 / NAM)</li> </ul> <p>Citation: Jung S. Bistable attractor dynamics in difficult-to-treat rheumatic disease: a multi-axis ODE framework with cross-disease transcriptomic consistency analysis. npj Systems Biology and Applications (under review, 2026).</p>