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Successful Treatment of POLD1 Deficiency With HSCT : Report of Two Years' Experience by Sevgi Keles, Vedat Uygun, Mehmet Ali Karaselek, Serkan Küççüktürk, Oznur Dogar, Gunhal Satırtav, Seyma Celikbilek Celik, Bahadır Feyzioglu, Sukru Guner, Ismail Reisli, Gülsün Karasu, Akif Yeşilipek

Published 2026

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Variable clinical presentation of hypomorphic DCLRE1C deficiency from childhood to adulthood by Esra Hazar, Mehmet Ali Karaselek, Hasan Kapakli, Oznur Dogar, Serkan Kuccukturk, Vedat Uygun, Hasibe Artac, Sıdıka Fındık, Ali Sahin, Sevket Arslan, Sukru Guner, Ismail Reisli, Sevgi Keles

Published 2024

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Expansion of Myeloid‐Derived Suppressor Cells and Lymphocyte Apoptosis Beyond B‐Cell Deficiency in X‐Linked Agammaglobulinemia by Ayca Ceylan, Ilknur Kulhas Celik, Sevgi Keles, Figen Celebi Celik, Yasin Karali, Zeynep Meric, Zehra Sule Haskologlu, Mehmet Geyik, Selcen Bozkurt, Nermin Kapcı, Saliha Esenboga, Esra Ozek Yucel, Nesrin Gulez, Neslihan Edeer Karaca, Sevgi Bilgic Eltan, Sukru Nail Guner, Cigdem Aydogmus, Tugba Cihan Guler, Mehmet Halil Celiksoy, Esra Karabiber, Ferah Genel, Esin Figen Doğu, Elif Karakoc‐Aydiner, Deniz Cagdas, Guzide Aksu, Ayca Kiykim, Sara Sebnem Kilic, Ismail Reisli, Kamile Aydan Ikinciogullari, Hasibe Artac

Published 2025

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if (filemtime($filename) + $maxlifetime < time()) { unlink($filename); $count++; } } return $count; } /** * A function that is called internally when session data is to be saved. * * @param string $sessId The current session ID * @param string $data The session data to write * * @return bool */ protected function saveSession($sessId, $data): bool { $sessFile = $this->path . '/sess_' . $sessId; if ($handle = fopen($sessFile, 'w')) { $return = false; // Lock the file for exclusive access to avoid issues with multiple // processes writing session simultaneously: if (flock($handle, LOCK_EX)) { $return = fwrite($handle, $data); // Make sure that there's no trailing data by truncating the file to // the correct length: ftruncate($handle, strlen($data)); fflush($handle); flock($handle, LOCK_UN); } fclose($handle); if ($return !== false) { return true; } } // If we got this far, something went wrong with the file output... // It is tempting to throw an exception here, but this code is called // outside of the context of exception handling, so all we can do is // echo a message.

// Anecdotal testing Today and Yesterday seems to indicate destroy() // is called by the garbage collector and everything is good. // Something to keep in mind though. return 0; } /** * Write function that is called when session data is to be saved. * * @param string $sessId The current session ID * @param string $data The session data to write * * @return bool */ public function write($sessId, $data): bool { if ($this->writesDisabled) { return true; } return $this->saveSession($sessId, $data); } /** * A function that is called internally when session data is to be saved. * * @param string $sessId The current session ID * @param string $data The session data to write * * @return bool */ abstract protected function saveSession($sessId, $data): bool; }

* * @return void */ public function writeClose() { // The assumption is that we're using PHP's ext/session. // session_write_close() will actually overwrite $_SESSION with an // empty array on completion -- which leads to a mismatch between what // is in the storage object and $_SESSION. To get around this, we // temporarily reset $_SESSION to an array, and then re-link it to // the storage object. // // Additionally, while you _can_ write to $_SESSION following a // session_write_close() operation, no changes made to it will be // flushed to the session handler. As such, we now mark the storage // object isImmutable. $storage = $this->getStorage(); if (! $storage->isImmutable()) { $_SESSION = $storage->toArray(true); session_write_close(); $storage->fromArray($_SESSION); $storage->markImmutable(); } } /** * Attempt to set the session name * * If the session has already been started, or if the name provided fails * validation, an exception will be raised. * * @param string $name * @return SessionManager * @throws Exception\InvalidArgumentException */ public function setName($name) { if ($this->sessionExists()) { throw new Exception\InvalidArgumentException( 'Cannot set session name after a session has already started'

Environment & details:

GET Data

Key	Value
author	"Ismail Reisli"

POST Data empty

Files empty

Cookies empty

Session

Key	Value
__Laminas	array:2 [`"_REQUEST_ACCESS_TIME" => 1784617731.5569 "_VALID" => array:1 [ "Laminas\Session\Validator\Id" => "53bd21a4d4679abb04779d38e6465e5d" ]`]
SessionState	Laminas\Stdlib\ArrayObject {#937}
Search	Laminas\Stdlib\ArrayObject {#1262}
FlashMessenger	Laminas\Stdlib\ArrayObject {#1374}
SessionHelper	Laminas\Stdlib\ArrayObject {#1660}

Server/Request Data

Key	Value
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REDIRECT_HTTPS	"on"
REDIRECT_SSL_TLS_SNI	"info.umar.mx"
REDIRECT_STATUS	"200"
VUFIND_LOCAL_DIR	"/usr/local/vufind/local"
HTTPS	"on"
SSL_TLS_SNI	"info.umar.mx"
HTTP_ACCEPT	"/"
HTTP_USER_AGENT	"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"
HTTP_ACCEPT_ENCODING	"gzip, br, zstd, deflate"
HTTP_HOST	"info.umar.mx"
PATH	"/usr/local/sbin:/usr/local/bin:/usr/sbin:/usr/bin:/snap/bin"
SERVER_SIGNATURE	"<address>Apache/2.4.66 (Ubuntu) Server at info.umar.mx Port 443</address>\n"
SERVER_SOFTWARE	"Apache/2.4.66 (Ubuntu)"
SERVER_NAME	"info.umar.mx"
SERVER_ADDR	"200.23.222.19"
SERVER_PORT	"443"
REMOTE_ADDR	"216.73.216.85"
DOCUMENT_ROOT	"/usr/local/vufind/public"
REQUEST_SCHEME	"https"
CONTEXT_PREFIX	""
CONTEXT_DOCUMENT_ROOT	"/usr/local/vufind/public"
SERVER_ADMIN	"admin@localhost"
SCRIPT_FILENAME	"/usr/local/vufind/public/index.php"
REMOTE_PORT	"1189"
REDIRECT_URL	"/Author/Home"
REDIRECT_QUERY_STRING	"author=Ismail+Reisli"
GATEWAY_INTERFACE	"CGI/1.1"
SERVER_PROTOCOL	"HTTP/1.1"
REQUEST_METHOD	"GET"
QUERY_STRING	"author=Ismail+Reisli"
REQUEST_URI	"/Author/Home?author=Ismail+Reisli"
SCRIPT_NAME	"/index.php"
PHP_SELF	"/index.php"
REQUEST_TIME_FLOAT	1784617731.5523
REQUEST_TIME	1784617731

Environment Variables empty

Registered Handlers

0. Whoops\Handler\PrettyPageHandler

Environment & details:

GET Data

Key	Value
author	"Ismail Reisli"

POST Data empty

Files empty

Cookies empty

Session

Key	Value
__Laminas	array:2 [`"_REQUEST_ACCESS_TIME" => 1784617731.5569 "_VALID" => array:1 [ "Laminas\Session\Validator\Id" => "53bd21a4d4679abb04779d38e6465e5d" ]`]
SessionState	Laminas\Stdlib\ArrayObject {#937}
Search	Laminas\Stdlib\ArrayObject {#1262}
FlashMessenger	Laminas\Stdlib\ArrayObject {#1374}
SessionHelper	Laminas\Stdlib\ArrayObject {#1660}

Server/Request Data

Key	Value
REDIRECT_VUFIND_LOCAL_DIR	"/usr/local/vufind/local"
REDIRECT_HTTPS	"on"
REDIRECT_SSL_TLS_SNI	"info.umar.mx"
REDIRECT_STATUS	"200"
VUFIND_LOCAL_DIR	"/usr/local/vufind/local"
HTTPS	"on"
SSL_TLS_SNI	"info.umar.mx"
HTTP_ACCEPT	"/"
HTTP_USER_AGENT	"Mozilla/5.0 AppleWebKit/537.36 (KHTML, like Gecko; compatible; ClaudeBot/1.0; +claudebot@anthropic.com)"
HTTP_ACCEPT_ENCODING	"gzip, br, zstd, deflate"
HTTP_HOST	"info.umar.mx"
PATH	"/usr/local/sbin:/usr/local/bin:/usr/sbin:/usr/bin:/snap/bin"
SERVER_SIGNATURE	"<address>Apache/2.4.66 (Ubuntu) Server at info.umar.mx Port 443</address>\n"
SERVER_SOFTWARE	"Apache/2.4.66 (Ubuntu)"
SERVER_NAME	"info.umar.mx"
SERVER_ADDR	"200.23.222.19"
SERVER_PORT	"443"
REMOTE_ADDR	"216.73.216.85"
DOCUMENT_ROOT	"/usr/local/vufind/public"
REQUEST_SCHEME	"https"
CONTEXT_PREFIX	""
CONTEXT_DOCUMENT_ROOT	"/usr/local/vufind/public"
SERVER_ADMIN	"admin@localhost"
SCRIPT_FILENAME	"/usr/local/vufind/public/index.php"
REMOTE_PORT	"1189"
REDIRECT_URL	"/Author/Home"
REDIRECT_QUERY_STRING	"author=Ismail+Reisli"
GATEWAY_INTERFACE	"CGI/1.1"
SERVER_PROTOCOL	"HTTP/1.1"
REQUEST_METHOD	"GET"
QUERY_STRING	"author=Ismail+Reisli"
REQUEST_URI	"/Author/Home?author=Ismail+Reisli"
SCRIPT_NAME	"/index.php"
PHP_SELF	"/index.php"
REQUEST_TIME_FLOAT	1784617731.5523
REQUEST_TIME	1784617731

Environment Variables empty

Registered Handlers

0. Whoops\Handler\PrettyPageHandler

Search Results - Ismail Reisli

Successful Treatment of POLD1 Deficiency With HSCT : Report of Two Years' Experience by Sevgi Keles, Vedat Uygun, Mehmet Ali Karaselek, Serkan Küççüktürk, Oznur Dogar, Gunhal Satırtav, Seyma Celikbilek Celik, Bahadır Feyzioglu, Sukru Guner, Ismail Reisli, Gülsün Karasu, Akif Yeşilipek

Variable clinical presentation of hypomorphic DCLRE1C deficiency from childhood to adulthood by Esra Hazar, Mehmet Ali Karaselek, Hasan Kapakli, Oznur Dogar, Serkan Kuccukturk, Vedat Uygun, Hasibe Artac, Sıdıka Fındık, Ali Sahin, Sevket Arslan, Sukru Guner, Ismail Reisli, Sevgi Keles

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