Search Results - Pallavi Sachdev

Characterization of Lewy Body copathology in early AD clinical trial population demonstrates similarities and differences compared to natural history studies in Alzheimer's disease... by David Verbel, Hongmei Niu, Larisa Reyderman, Michael C. Irizarry, Pallavi Sachdev

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A de novo ‐assisted strategy to identify novel lncRNA‐encoded peptides in cerebrospinal fluid of demented subjects with or without amyloid positivity by Satya Saxena, Yuanqing Ye, Viswanath Devanarayan, Larisa Reyderman, Kristin R Wildsmith, Pallavi Sachdev

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Identifying differentially expressed proteins between amyloid positive and amyloid negative subjects based on Alamar multiplex assay data using MissionAD samples by Pallavi Sachdev, Han Yin, Hongmei Niu, Larisa Reyderman, Michael C. Irizarry, David Verbel

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Long‐Term Effects of Lecanemab on Biomarkers of Neurodegeneration in Plasma by Charlotte Teunissen, Brian A. Willis, Pratik Bhagunde, Robert Bell, Natasha Penner, Pallavi Sachdev, Larisa Reyderman

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"Paradoxical” Cerebral Volume Changes in Anti‐Amyloid Immunotherapy Trials by Nick C Fox, Arnaud Charil, Pallavi Sachdev, Hongmei Niu, Michael C. Irizarry, Steven Hersch, Larisa Reyderman

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Neuro‐Dynamic Quantitative Systems Pharmacology (Qsp) Model Supports Continued Lecanemab Treatment With Maintenance Dosing For Alzheimer’s Disease by Youfang Cao, Brian A. Willis, Pallavi Sachdev, Natasha Penner, Kristin R Wildsmith, Arnaud Charil, Kanta Horie, Akihiko Koyama, Larisa Reyderman

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Pharmacokinetic/pharmacodynamic analyses of plasma pathophysiology biomarkers in subjects with early Alzheimer's disease following lecanemab treatment by Pratik Bhagunde, Natasha Penner, Brian A. Willis, Robert Bell, Pallavi Sachdev, Arnaud Charil, Michael C. Irizarry, Steven Hersch, Larisa Reyderman

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Combining CSF MTBR‐tau243 and plasma pTau217 ratio enhances the prediction of continuous regional tau PET burden in early Alzheimer's disease by Viswanath Devanarayan, Kanta Horie, Kristin Wildsmith, Thomas Doherty, Erica Andreozzi, Arnaud Charil, Pallavi Sachdev, Lynn D. Kramer, Shobha Dhadda, Michael C. Irizarry

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Target Engagement of Lecanemab on CSF Aβ Protofibril Toxic Species in Clarity AD by Kanta Horie, Akihiko Koyama, Pallavi Sachdev, Kazuyoshi Shuta, Kazuhiro Tahara, Michio Kanekiyo, Shobha Dhadda, Larisa Reyderman, Steven Hersch, Michael C. Irizarry, Lynn D Kramer

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Lecanemab Slows Amyloid‐Induced Tau Pathology as Supported by CSF MTBR‐tau243 in Clarity AD by Kristin R Wildsmith, Pallavi Sachdev, Kanta Horie, Larisa Reyderman, Arnaud Charil, Michio Kanekiyo, Han Yin, David Li, Akihiko Koyama, Shobha Dhadda, Michael C. Irizarry, Lynn D Kramer

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Prediction of regional brain tau levels in early Alzheimer’s disease using plasma pTau217 by Viswanath Devanarayan, Arnaud Charil, Thomas Doherty, Daniel A. Llano, Yuanqing Ye, Erica Andreozzi, Jin Zhou, Pallavi Sachdev, Larisa Reyderman, Harald Hampel, Lynn D Kramer, Shobha Dhadda, Michael C. Irizarry

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Plasma pTau217 predicts continuous brain amyloid levels in preclinical and early Alzheimer's disease by Viswanath Devanarayan, Thomas Doherty, Arnaud Charil, Pallavi Sachdev, Yuanqing Ye, Leema Krishna Murali, Daniel A. Llano, Jin Zhou, Larisa Reyderman, Harald Hampel, Lynn D. Kramer, Shobha Dhadda, Michael C. Irizarry

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In vivo biomarkers of GABAergic function in epileptic rats treated with the GAT‐1 inhibitor E2730 by Idrish Ali, Bianca Jupp, Matthew R. Hudson, Brendan Major, Juliana Silva, Glenn R. Yamakawa, Pablo M. Casillas‐Espinosa, Emma Braine, Peravina Thergarajan, Mohammad B. Haskali, Lucy Vivash, Robert Brkljaca, Sandy R. Shultz, Patrick Kwan, Kazuyuki Fukushima, Pallavi Sachdev, Jocelyn Y. Cheng, Richelle Mychasiuk, Nigel C. Jones, David K. Wright, Terence J. OBrien

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Clinical validation of the PrecivityAD2 blood test: A mass spectrometry‐based test with algorithm combining %p‐tau217 and Aβ42/40 ratio to identify presence of brain amyloid by Matthew R. Meyer, Kristopher M. Kirmess, Stephanie Eastwood, Traci L. Wente‐Roth, Faith Irvin, Mary S. Holubasch, Venky Venkatesh, Ilana Fogelman, Mark Monane, Lucy Hanna, Gil D. Rabinovici, Barry A. Siegel, Rachel A. Whitmer, Charles Apgar, Randall J. Bateman, David M. Holtzman, Michael Irizarry, David Verbel, Pallavi Sachdev, Satoshi Ito, John Contois, Kevin E. Yarasheski, Joel B. Braunstein, Philip B. Verghese, Tim West

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