Search Results - Sebastian Frechen
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In‐Depth Analysis of the Selection of PBPK Modeling Tools: Bibliometric and Social Network Analysis of the Open Systems Pharmacology Community Autoría: André Dallmann, Donato Teutonico, Stephan Schaller, Rolf Burghaus, Sebastian Frechen
Published 2024Fuente: Wiley Open AccessTipo de material: Artículo Open AccessAcceso al recurso -
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PBPK modeling: What is the role of CYP3A4 expression in the gastrointestinal tract to accurately predict first‐pass metabolism? Autoría: Justine Henriot, André Dallmann, François Dupuis, Jérémy Perrier, Sebastian Frechen
Published 2024Fuente: Wiley Open AccessTipo de material: Artículo Open AccessAcceso al recurso -
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Assessment of the CYP3A4 Induction Potential by Carbamazepine: Insights from Two Clinical DDI Studies and PBPK Modeling Autoría: Friederike Kanefendt, André Dallmann, Huijun Chen, Klaus Francke, Tianxing Liu, Christine Brase, Sebastian Frechen, Marcus‐Hillert Schultze‐Mosgau
Published 2024Fuente: Wiley Open AccessTipo de material: Artículo Open AccessAcceso al recurso -
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Population pharmacokinetic–pharmacodynamic model of elinzanetant based on integrated clinical phase I and II data Autoría: Stefan Willmann, Adam Lloyd, Rupert Austin, Shiju Joseph, Alexander Solms, Yang Zhang, Annika R. P. Schneider, Sebastian Frechen, Marcus‐Hillert Schultze‐Mosgau
Published 2024Fuente: Wiley Open AccessTipo de material: Artículo Open AccessAcceso al recurso -
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A Comprehensive CYP2D6 Drug–Drug–Gene Interaction Network for Application in Precision Dosing and Drug Development Autoría: Simeon Rüdesheim, Helena Leonie Hanae Loer, Denise Feick, Fatima Zahra Marok, Laura Maria Fuhr, Dominik Selzer, Donato Teutonico, Annika R. P. Schneider, Juri Solodenko, Sebastian Frechen, Maaike van der Lee, Dirk Jan A. R. Moes, Jesse J. Swen, Matthias Schwab, Thorsten Lehr
Published 2025Fuente: Wiley Open AccessTipo de material: Artículo Open AccessAcceso al recurso