Causal inference using invariant prediction: identification and confidence intervals

Fuente: arXiv
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Hauptverfasser: Peters, Jonas, Bühlmann, Peter, Meinshausen, Nicolai
Format: Preprint
Veröffentlicht: 2015
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author Peters, Jonas
Bühlmann, Peter
Meinshausen, Nicolai
author_facet Peters, Jonas
Bühlmann, Peter
Meinshausen, Nicolai
contents What is the difference of a prediction that is made with a causal model and a non-causal model? Suppose we intervene on the predictor variables or change the whole environment. The predictions from a causal model will in general work as well under interventions as for observational data. In contrast, predictions from a non-causal model can potentially be very wrong if we actively intervene on variables. Here, we propose to exploit this invariance of a prediction under a causal model for causal inference: given different experimental settings (for example various interventions) we collect all models that do show invariance in their predictive accuracy across settings and interventions. The causal model will be a member of this set of models with high probability. This approach yields valid confidence intervals for the causal relationships in quite general scenarios. We examine the example of structural equation models in more detail and provide sufficient assumptions under which the set of causal predictors becomes identifiable. We further investigate robustness properties of our approach under model misspecification and discuss possible extensions. The empirical properties are studied for various data sets, including large-scale gene perturbation experiments.
format Preprint
id arxiv_https___arxiv_org_abs_1501_01332
institution arXiv
publishDate 2015
record_format arxiv
spellingShingle Causal inference using invariant prediction: identification and confidence intervals
Peters, Jonas
Bühlmann, Peter
Meinshausen, Nicolai
Methodology
Machine Learning
What is the difference of a prediction that is made with a causal model and a non-causal model? Suppose we intervene on the predictor variables or change the whole environment. The predictions from a causal model will in general work as well under interventions as for observational data. In contrast, predictions from a non-causal model can potentially be very wrong if we actively intervene on variables. Here, we propose to exploit this invariance of a prediction under a causal model for causal inference: given different experimental settings (for example various interventions) we collect all models that do show invariance in their predictive accuracy across settings and interventions. The causal model will be a member of this set of models with high probability. This approach yields valid confidence intervals for the causal relationships in quite general scenarios. We examine the example of structural equation models in more detail and provide sufficient assumptions under which the set of causal predictors becomes identifiable. We further investigate robustness properties of our approach under model misspecification and discuss possible extensions. The empirical properties are studied for various data sets, including large-scale gene perturbation experiments.
title Causal inference using invariant prediction: identification and confidence intervals
topic Methodology
Machine Learning
url https://arxiv.org/abs/1501.01332