Buchumschlag

Phenotypic divergence of Homo sapiens is driven by the evolution of human-specific genomic regulatory networks via two mechanistically distinct pathways of creation of divergent regulatory DNA sequences

Fuente: arXiv

Gespeichert in:

Bibliographische Detailangaben
1. Verfasser:	Glinsky, Gennadi
Format:	Preprint
Veröffentlicht:	2015
Schlagworte:	Genomics
Online-Zugang:	Acceder al recurso
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge

Analysis of evolutionary origins of genomic loci harboring 59,732 candidate human-specific regulatory sequences identifies genetic divergence patterns during evolution of Great Apes
von: Glinsky, Gennadi
Veröffentlicht: (2018)

Highly conserved sequence-specific double-stranded DNA binding networks contributing to divergent genomic evolution of human and chimpanzee brain development
von: Glinsky, Gennadi
Veröffentlicht: (2024)

Identification and characterization of unique to human regulatory sequences in embryonic stem cells reveal associations with transposable elements, distal enhancers, non-coding RNA, and DNA methylation-driven mechanisms of genome editing
von: Glinsky, Gennadi
Veröffentlicht: (2014)

A genomic dominion with regulatory dependencies on human-specific single-nucleotide changes in Modern Humans
von: Glinsky, Gennadi V.
Veröffentlicht: (2019)

Genomic regulatory architecture of human embryo retroviral LTR elements affecting evolution, development, and pathophysiology of Modern Humans
von: Glinsky, Gennadi
Veröffentlicht: (2023)

Genomics-guided drawing of malignant regulatory signatures revealed a pivotal role of human stem cell-associated retroviral sequences (SCARS) and functionally-active hESC enhancers
von: Glinsky, Gennadi
Veröffentlicht: (2020)

Role of distal enhancers in shaping 3D-folding patterns and defining human-specific features of interphase chromatin architecture in embryonic stem cells
von: Glinsky, Gennadi
Veröffentlicht: (2017)

A mechanistically interpretable neural network for regulatory genomics
von: Tseng, Alex M., et al.
Veröffentlicht: (2024)

Homo sapiens-specific evolution unveiled by ancient southern African genomes.
von: Jakobsson, Mattias, et al.
Veröffentlicht: (2026)

Perspective on recent developments and challenges in regulatory and systems genomics
von: Zeiltinger, Julia, et al.
Veröffentlicht: (2024)

inMOTIFin: a lightweight end-to-end simulation software for regulatory sequences
von: Ferenc, Katalin, et al.
Veröffentlicht: (2025)

Approximating a gene regulatory network from non-sequential data
von: Stein, Cliff, et al.
Veröffentlicht: (2024)

Addressing missing context in regulatory variation across primate evolution
von: Housman, Genevieve, et al.
Veröffentlicht: (2025)

Insights into cephalochordate genome and gene evolution from the early-diverging amphioxus .
von: Ren, Yifan, et al.
Veröffentlicht: (2026)

Causes of evolutionary divergence in prostate cancer
von: Esenturk, Emre, et al.
Veröffentlicht: (2025)

Approaches for benchmarking single-cell gene regulatory network inference methods
von: Uzun, Yasin
Veröffentlicht: (2023)

Reference genome for the benthic marine diatom Psammoneis japonica: Bacterial associations and repeat-driven genome size evolution in diatoms.
von: Roberts, Wade R, et al.
Veröffentlicht: (2025)

Geographic divergence in population genomics and shell morphology reveal history of glacial refugia in a coastal dogwhelk.
von: Longman, Emily K, et al.
Veröffentlicht: (2026)

Predicting the genetic component of gene expression using gene regulatory networks
von: Mohammad, Gutama Ibrahim, et al.
Veröffentlicht: (2024)

Hemichordate cis-regulatory genomics and the gene expression dynamics of deuterostomes.
von: Pérez-Posada, Alberto, et al.
Veröffentlicht: (2024)

The telomere-to-telomere (T2T) genome provides insights into the evolution of specialized centromere sequences in sandalwood.
von: Peng, Dan, et al.
Veröffentlicht: (2024)

Integrated GWAS and Fst analysis identify flowering‐time regulatory genes in maize
von: Dong Wang, et al.
Veröffentlicht: (2026)

skandiver: a divergence-based analysis tool for identifying intercellular mobile genetic elements
von: Zhang, Xiaolei Brian, et al.
Veröffentlicht: (2024)

Deciphering regulatory architectures from synthetic single-cell expression patterns
von: Pan, Rosalind Wenshan, et al.
Veröffentlicht: (2024)

Identification of sex-specific markers using genome re-sequencing in the blunt snout bream (Megalobrama amblycephala).
von: Fu, Yuye, et al.
Veröffentlicht: (2024)

Deep conservation of cis-regulatory elements and chromatin organization in echinoderms uncover ancestral regulatory features of animal genomes.
von: Magri, Marta S, et al.
Veröffentlicht: (2026)

A novel cable bacteria species with a distinct morphology and genomic potential.
von: Hiralal, Anwar, et al.
Veröffentlicht: (2025)

Shotgun DNA sequencing for human identification: Dynamic SNP selection and likelihood ratio calculations accounting for errors
von: Andersen, Mikkel Meyer, et al.
Veröffentlicht: (2024)

Finding low-complexity DNA sequences with longdust
von: Li, Heng, et al.
Veröffentlicht: (2025)

Complete genome sequence of Lysinibacillus sp. WB86, a potential antimicrobial lanthipeptides producer.
von: Sun, Huai-Ying, et al.
Veröffentlicht: (2025)

Exploring the regulatory potential of RNA structures in 202 cyanobacterial genomes.
von: Geissler, Adrian Sven, et al.
Veröffentlicht: (2026)

The draft genome sequences of the cosmopolitan centric diatom, the genus Skeletonema.
von: Nagai, Satoshi, et al.
Veröffentlicht: (2025)

Adaptive genomic divergence parallels migratory behavior in Atlantic bluefin tuna.
von: Mikles, Chloe S, et al.
Veröffentlicht: (2026)

Evaluating DNA function understanding in genomic language models using evolutionarily implausible sequences
von: Jiang, Shiyu, et al.
Veröffentlicht: (2025)

Just-DNA-Seq, open-source personal genomics platform: longevity science for everyone
von: Anton, Kulaga, et al.
Veröffentlicht: (2024)

A low‐coverage skim‐sequencing and imputation pipeline for genomic selection
von: Sajal R. Sthapit, et al.
Veröffentlicht: (2025)

Complete sequencing of ape genomes.
von: Yoo, DongAhn, et al.
Veröffentlicht: (2025)

Informational blueprints reveal condition-dependent gene regulatory architectures
von: Gökmen, Doruk Efe, et al.
Veröffentlicht: (2026)

Complete genome sequence of the marine mangrove fungus Sarcopodium sp.QM3-1 confirmed its high potential for antimicrobial activity.
von: Zhang, Wenzhou, et al.
Veröffentlicht: (2025)

Dissecting the genomic regions, candidate genes and pathways using multi‐locus genome‐wide association study for stem rot disease resistance in groundnut
von: H. V. Veerendrakumar, et al.
Veröffentlicht: (2025)