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Bibliographic Details
Main Authors: Cortes-Poza, Yuriria, Perez-Buendia, J. Rogelio
Format: Preprint
Published: 2019
Subjects:
Online Access:https://arxiv.org/abs/1903.09386
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Table of Contents:
  • Morphogenesis is the biological process that causes the emergence and changes of patterns (tissues and organs) in living organisms. It is a robust, self-organising mechanism, governed by Genetic Regulatory Networks (GRN), that hasn't been thoroughly understood. In this work we propose Epigenetic Forests as a tool to study morphogenesis and to extract valuable information from GRN. Our method unfolds the richness and structure within the GRN. As a case study, we analyze the GRN during cell fate determination during the early stages of development of the flower Arabidopsis thaliana and its spatial dynamics. By using a genetic algorithm we optimize cell differentiation in our model and correctly recover the architecture of the flower.