Stain Style Transfer using Transitive Adversarial Networks

Fuente: arXiv
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Autores principales: Cai, Shaojin, Gao, Yuyang Xue3 Qinquan, Du, Min, Chen, Gang, Zhang, Hejun, Tong, Tong
Formato: Preprint
Publicado: 2019
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author Cai, Shaojin
Gao, Yuyang Xue3 Qinquan
Du, Min
Chen, Gang
Zhang, Hejun
Tong, Tong
author_facet Cai, Shaojin
Gao, Yuyang Xue3 Qinquan
Du, Min
Chen, Gang
Zhang, Hejun
Tong, Tong
contents Digitized pathological diagnosis has been in increasing demand recently. It is well known that color information is critical to the automatic and visual analysis of pathological slides. However, the color variations due to various factors not only have negative impact on pathologist's diagnosis, but also will reduce the robustness of the algorithms. The factors that cause the color differences are not only in the process of making the slices, but also in the process of digitization. Different strategies have been proposed to alleviate the color variations. Most of such techniques rely on collecting color statistics to perform color matching across images and highly dependent on a reference template slide. Since the pathological slides between hospitals are usually unpaired, these methods do not yield good matching results. In this work, we propose a novel network that we refer to as Transitive Adversarial Networks (TAN) to transfer the color information among slides from different hospitals or centers. It is not necessary for an expert to pick a representative reference slide in the proposed TAN method. We compare the proposed method with the state-of-the-art methods quantitatively and qualitatively. Compared with the state-of-the-art methods, our method yields an improvement of 0.87dB in terms of PSNR, demonstrating the effectiveness of the proposed TAN method in stain style transfer.
format Preprint
id arxiv_https___arxiv_org_abs_1910_10330
institution arXiv
publishDate 2019
record_format arxiv
spellingShingle Stain Style Transfer using Transitive Adversarial Networks
Cai, Shaojin
Gao, Yuyang Xue3 Qinquan
Du, Min
Chen, Gang
Zhang, Hejun
Tong, Tong
Image and Video Processing
Computer Vision and Pattern Recognition
Digitized pathological diagnosis has been in increasing demand recently. It is well known that color information is critical to the automatic and visual analysis of pathological slides. However, the color variations due to various factors not only have negative impact on pathologist's diagnosis, but also will reduce the robustness of the algorithms. The factors that cause the color differences are not only in the process of making the slices, but also in the process of digitization. Different strategies have been proposed to alleviate the color variations. Most of such techniques rely on collecting color statistics to perform color matching across images and highly dependent on a reference template slide. Since the pathological slides between hospitals are usually unpaired, these methods do not yield good matching results. In this work, we propose a novel network that we refer to as Transitive Adversarial Networks (TAN) to transfer the color information among slides from different hospitals or centers. It is not necessary for an expert to pick a representative reference slide in the proposed TAN method. We compare the proposed method with the state-of-the-art methods quantitatively and qualitatively. Compared with the state-of-the-art methods, our method yields an improvement of 0.87dB in terms of PSNR, demonstrating the effectiveness of the proposed TAN method in stain style transfer.
title Stain Style Transfer using Transitive Adversarial Networks
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/1910.10330