The structure of the moduli space of toric dynamical systems of a reaction network

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Main Authors: Craciun, Gheorghe, Jin, Jiaxin, Sorea, Miruna-Stefana
Format: Preprint
Published: 2020
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author Craciun, Gheorghe
Jin, Jiaxin
Sorea, Miruna-Stefana
author_facet Craciun, Gheorghe
Jin, Jiaxin
Sorea, Miruna-Stefana
contents We consider toric dynamical systems, which are also called complex-balanced mass-action systems. These are remarkably stable polynomial dynamical systems that arise from the analysis of mathematical models of reaction networks when, under the assumption of mass-action kinetics, they can give rise to complex-balanced equilibria. Given a reaction network, we study the moduli space of toric dynamical systems generated by this network, also called the toric locus of the network. The toric locus is an algebraic variety, and we are especially interested in its topological properties. We show that complex-balanced equilibria depend continuously on the parameter values in the toric locus, and, using this result, we prove that the toric locus has a remarkable product structure: it is homeomorphic to the product of the set of complex-balanced flux vectors and the affine invariant polyhedron of the network. In particular, it follows that the toric locus is a contractible manifold. Finally, we show that the toric locus is invariant with respect to bijective affine transformations of the generating reaction network.
format Preprint
id arxiv_https___arxiv_org_abs_2008_11468
institution arXiv
publishDate 2020
record_format arxiv
spellingShingle The structure of the moduli space of toric dynamical systems of a reaction network
Craciun, Gheorghe
Jin, Jiaxin
Sorea, Miruna-Stefana
Algebraic Geometry
Dynamical Systems
14P05, 14P10, 14Q30, 34D23, 34C08, 37E99, 92C42,
We consider toric dynamical systems, which are also called complex-balanced mass-action systems. These are remarkably stable polynomial dynamical systems that arise from the analysis of mathematical models of reaction networks when, under the assumption of mass-action kinetics, they can give rise to complex-balanced equilibria. Given a reaction network, we study the moduli space of toric dynamical systems generated by this network, also called the toric locus of the network. The toric locus is an algebraic variety, and we are especially interested in its topological properties. We show that complex-balanced equilibria depend continuously on the parameter values in the toric locus, and, using this result, we prove that the toric locus has a remarkable product structure: it is homeomorphic to the product of the set of complex-balanced flux vectors and the affine invariant polyhedron of the network. In particular, it follows that the toric locus is a contractible manifold. Finally, we show that the toric locus is invariant with respect to bijective affine transformations of the generating reaction network.
title The structure of the moduli space of toric dynamical systems of a reaction network
topic Algebraic Geometry
Dynamical Systems
14P05, 14P10, 14Q30, 34D23, 34C08, 37E99, 92C42,
url https://arxiv.org/abs/2008.11468