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Main Authors: Tan, Jeremy, Hou, Benjamin, Batten, James, Qiu, Huaqi, Kainz, Bernhard
Format: Preprint
Published: 2020
Subjects:
Online Access:https://arxiv.org/abs/2011.04197
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author Tan, Jeremy
Hou, Benjamin
Batten, James
Qiu, Huaqi
Kainz, Bernhard
author_facet Tan, Jeremy
Hou, Benjamin
Batten, James
Qiu, Huaqi
Kainz, Bernhard
contents In medical imaging, outliers can contain hypo/hyper-intensities, minor deformations, or completely altered anatomy. To detect these irregularities it is helpful to learn the features present in both normal and abnormal images. However this is difficult because of the wide range of possible abnormalities and also the number of ways that normal anatomy can vary naturally. As such, we leverage the natural variations in normal anatomy to create a range of synthetic abnormalities. Specifically, the same patch region is extracted from two independent samples and replaced with an interpolation between both patches. The interpolation factor, patch size, and patch location are randomly sampled from uniform distributions. A wide residual encoder decoder is trained to give a pixel-wise prediction of the patch and its interpolation factor. This encourages the network to learn what features to expect normally and to identify where foreign patterns have been introduced. The estimate of the interpolation factor lends itself nicely to the derivation of an outlier score. Meanwhile the pixel-wise output allows for pixel- and subject- level predictions using the same model.
format Preprint
id arxiv_https___arxiv_org_abs_2011_04197
institution arXiv
publishDate 2020
record_format arxiv
spellingShingle Detecting Outliers with Foreign Patch Interpolation
Tan, Jeremy
Hou, Benjamin
Batten, James
Qiu, Huaqi
Kainz, Bernhard
Computer Vision and Pattern Recognition
In medical imaging, outliers can contain hypo/hyper-intensities, minor deformations, or completely altered anatomy. To detect these irregularities it is helpful to learn the features present in both normal and abnormal images. However this is difficult because of the wide range of possible abnormalities and also the number of ways that normal anatomy can vary naturally. As such, we leverage the natural variations in normal anatomy to create a range of synthetic abnormalities. Specifically, the same patch region is extracted from two independent samples and replaced with an interpolation between both patches. The interpolation factor, patch size, and patch location are randomly sampled from uniform distributions. A wide residual encoder decoder is trained to give a pixel-wise prediction of the patch and its interpolation factor. This encourages the network to learn what features to expect normally and to identify where foreign patterns have been introduced. The estimate of the interpolation factor lends itself nicely to the derivation of an outlier score. Meanwhile the pixel-wise output allows for pixel- and subject- level predictions using the same model.
title Detecting Outliers with Foreign Patch Interpolation
topic Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2011.04197