Weak convergence of the scaled jump chain and number of mutations of the Kingman coalescent

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Auteurs principaux: Favero, Martina, Hult, Henrik
Format: Preprint
Publié: 2020
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author Favero, Martina
Hult, Henrik
author_facet Favero, Martina
Hult, Henrik
contents The Kingman coalescent is a fundamental process in population genetics modelling the ancestry of a sample of individuals backwards in time. In this paper, in a large-sample-size regime, we study asymptotic properties of the coalescent under neutrality and a general finite-alleles mutation scheme, i.e. including both parent independent and parent dependent mutation. In particular, we consider a sequence of Markov chains that is related to the coalescent and consists of block-counting and mutation-counting components. We show that these components, suitably scaled, converge weakly to deterministic components and Poisson processes with varying intensities, respectively. Along the way, we develop a novel approach, based on a change of measure, to generalise the convergence result from the parent independent to the parent dependent mutation setting, in which several crucial quantities are not known explicitly.
format Preprint
id arxiv_https___arxiv_org_abs_2011_06908
institution arXiv
publishDate 2020
record_format arxiv
spellingShingle Weak convergence of the scaled jump chain and number of mutations of the Kingman coalescent
Favero, Martina
Hult, Henrik
Probability
60J90 (Primary) 60F05, 92D15 (Secondary)
The Kingman coalescent is a fundamental process in population genetics modelling the ancestry of a sample of individuals backwards in time. In this paper, in a large-sample-size regime, we study asymptotic properties of the coalescent under neutrality and a general finite-alleles mutation scheme, i.e. including both parent independent and parent dependent mutation. In particular, we consider a sequence of Markov chains that is related to the coalescent and consists of block-counting and mutation-counting components. We show that these components, suitably scaled, converge weakly to deterministic components and Poisson processes with varying intensities, respectively. Along the way, we develop a novel approach, based on a change of measure, to generalise the convergence result from the parent independent to the parent dependent mutation setting, in which several crucial quantities are not known explicitly.
title Weak convergence of the scaled jump chain and number of mutations of the Kingman coalescent
topic Probability
60J90 (Primary) 60F05, 92D15 (Secondary)
url https://arxiv.org/abs/2011.06908