Ultrasound Scatterer Density Classification Using Convolutional Neural Networks by Exploiting Patch Statistics

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Main Authors: Tehrani, Ali K. Z., Amiri, Mina, Rosado-Mendez, Ivan M., Hall, Timothy J., Rivaz, Hassan
Format: Preprint
Published: 2020
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author Tehrani, Ali K. Z.
Amiri, Mina
Rosado-Mendez, Ivan M.
Hall, Timothy J.
Rivaz, Hassan
author_facet Tehrani, Ali K. Z.
Amiri, Mina
Rosado-Mendez, Ivan M.
Hall, Timothy J.
Rivaz, Hassan
contents Quantitative ultrasound (QUS) can reveal crucial information on tissue properties such as scatterer density. If the scatterer density per resolution cell is above or below 10, the tissue is considered as fully developed speckle (FDS) or low-density scatterers (LDS), respectively. Conventionally, the scatterer density has been classified using estimated statistical parameters of the amplitude of backscattered echoes. However, if the patch size is small, the estimation is not accurate. These parameters are also highly dependent on imaging settings. In this paper, we propose a convolutional neural network (CNN) architecture for QUS, and train it using simulation data. We further improve the network performance by utilizing patch statistics as additional input channels. We evaluate the network using simulation data, experimental phantoms and in vivo data. We also compare our proposed network with different classic and deep learning models, and demonstrate its superior performance in classification of tissues with different scatterer density values. The results also show that the proposed network is able to work with different imaging parameters with no need for a reference phantom. This work demonstrates the potential of CNNs in classifying scatterer density in ultrasound images.
format Preprint
id arxiv_https___arxiv_org_abs_2012_02738
institution arXiv
publishDate 2020
record_format arxiv
spellingShingle Ultrasound Scatterer Density Classification Using Convolutional Neural Networks by Exploiting Patch Statistics
Tehrani, Ali K. Z.
Amiri, Mina
Rosado-Mendez, Ivan M.
Hall, Timothy J.
Rivaz, Hassan
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
Quantitative ultrasound (QUS) can reveal crucial information on tissue properties such as scatterer density. If the scatterer density per resolution cell is above or below 10, the tissue is considered as fully developed speckle (FDS) or low-density scatterers (LDS), respectively. Conventionally, the scatterer density has been classified using estimated statistical parameters of the amplitude of backscattered echoes. However, if the patch size is small, the estimation is not accurate. These parameters are also highly dependent on imaging settings. In this paper, we propose a convolutional neural network (CNN) architecture for QUS, and train it using simulation data. We further improve the network performance by utilizing patch statistics as additional input channels. We evaluate the network using simulation data, experimental phantoms and in vivo data. We also compare our proposed network with different classic and deep learning models, and demonstrate its superior performance in classification of tissues with different scatterer density values. The results also show that the proposed network is able to work with different imaging parameters with no need for a reference phantom. This work demonstrates the potential of CNNs in classifying scatterer density in ultrasound images.
title Ultrasound Scatterer Density Classification Using Convolutional Neural Networks by Exploiting Patch Statistics
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2012.02738