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Bibliographic Details
Main Authors: Kreiss, Alexander, Van Keilegom, Ingrid
Format: Preprint
Published: 2020
Subjects:
Online Access:https://arxiv.org/abs/2012.15611
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Table of Contents:
  • In epidemics many interesting quantities, like the reproduction number, depend on the incubation period (time from infection to symptom onset) and/or the generation time (time until a new person is infected from another infected person). Therefore, estimation of the distribution of these two quantities is of distinct interest. However, this is a challenging problem since it is normally not possible to obtain precise observations of these two variables. Instead, in the beginning of a pandemic, it is possible to observe for infection pairs the time of symptom onset for both people as well as a window for infection of the first person (e.g. because of travel to a risk area). In this paper we suggest a simple semi-parametric sieve-estimation method based on Laguerre-Polynomials for estimation of these distributions. We provide detailed theory for consistency and illustrate the finite sample performance for small datasets via a simulation study.