Towards Understanding the COVID-19 Case Fatality Rate

Fuente: arXiv
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Autori principali: Yan, Donghui, Chen, Aiyou, Yang, Buqing
Natura: Preprint
Pubblicazione: 2021
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author Yan, Donghui
Chen, Aiyou
Yang, Buqing
author_facet Yan, Donghui
Chen, Aiyou
Yang, Buqing
contents An important parameter for COVID-19 is the case fatality rate (CFR). It has been applied to wide applications, including the measure of the severity of the infection, the estimation of the number of infected cases, risk assessment etc. However, there remains a lack of understanding on several aspects of CFR, including population factors that are important to CFR, the apparent discrepancy of CFRs in different countries, and how the age effect comes into play. We analyze the CFRs at two different time snapshots, July 6 and Dec 28, 2020, with one during the first wave and the other a second wave of the COVID-19 pandemic. We consider two important population covariates, age and GDP as a proxy for the quality and abundance of public health. Extensive exploratory data analysis leads to some interesting findings. First, there is a clear exponential age effect among different age groups, and, more importantly, the exponential index is almost invariant across countries and time in the pandemic. Second, the roles played by the age and GDP are a little surprising: during the first wave, age is a more significant factor than GDP, while their roles have switched during the second wave of the pandemic, which may be partially explained by the delay in time for the quality and abundance of public health and medical research to factor in.
format Preprint
id arxiv_https___arxiv_org_abs_2103_01313
institution arXiv
publishDate 2021
record_format arxiv
spellingShingle Towards Understanding the COVID-19 Case Fatality Rate
Yan, Donghui
Chen, Aiyou
Yang, Buqing
Applications
Computers and Society
Other Quantitative Biology
An important parameter for COVID-19 is the case fatality rate (CFR). It has been applied to wide applications, including the measure of the severity of the infection, the estimation of the number of infected cases, risk assessment etc. However, there remains a lack of understanding on several aspects of CFR, including population factors that are important to CFR, the apparent discrepancy of CFRs in different countries, and how the age effect comes into play. We analyze the CFRs at two different time snapshots, July 6 and Dec 28, 2020, with one during the first wave and the other a second wave of the COVID-19 pandemic. We consider two important population covariates, age and GDP as a proxy for the quality and abundance of public health. Extensive exploratory data analysis leads to some interesting findings. First, there is a clear exponential age effect among different age groups, and, more importantly, the exponential index is almost invariant across countries and time in the pandemic. Second, the roles played by the age and GDP are a little surprising: during the first wave, age is a more significant factor than GDP, while their roles have switched during the second wave of the pandemic, which may be partially explained by the delay in time for the quality and abundance of public health and medical research to factor in.
title Towards Understanding the COVID-19 Case Fatality Rate
topic Applications
Computers and Society
Other Quantitative Biology
url https://arxiv.org/abs/2103.01313