Multiple conditional randomization tests for lagged and spillover treatment effects

Fuente: arXiv
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Auteurs principaux: Zhang, Yao, Zhao, Qingyuan
Format: Preprint
Publié: 2021
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author Zhang, Yao
Zhao, Qingyuan
author_facet Zhang, Yao
Zhao, Qingyuan
contents We consider the problem of constructing multiple independent conditional randomization tests using a single dataset. Because the tests are independent, the randomization p-values can be interpreted individually and combined using standard methods for multiple testing. We give a simple, sequential construction of such tests, and then discuss its application to three problems: Rosenbaum's evidence factors for observational studies, lagged treatment effect in stepped-wedge trials, and spillover effect in randomized trials with interference. We compare the proposed approach with some existing methods using simulated and real datasets. Finally, we establish a more general sufficient condition for independent conditional randomization tests.
format Preprint
id arxiv_https___arxiv_org_abs_2104_10618
institution arXiv
publishDate 2021
record_format arxiv
spellingShingle Multiple conditional randomization tests for lagged and spillover treatment effects
Zhang, Yao
Zhao, Qingyuan
Statistics Theory
Methodology
62G10, 62B15
We consider the problem of constructing multiple independent conditional randomization tests using a single dataset. Because the tests are independent, the randomization p-values can be interpreted individually and combined using standard methods for multiple testing. We give a simple, sequential construction of such tests, and then discuss its application to three problems: Rosenbaum's evidence factors for observational studies, lagged treatment effect in stepped-wedge trials, and spillover effect in randomized trials with interference. We compare the proposed approach with some existing methods using simulated and real datasets. Finally, we establish a more general sufficient condition for independent conditional randomization tests.
title Multiple conditional randomization tests for lagged and spillover treatment effects
topic Statistics Theory
Methodology
62G10, 62B15
url https://arxiv.org/abs/2104.10618