LENAS: Learning-based Neural Architecture Search and Ensemble for 3D Radiotherapy Dose Prediction

Fuente: arXiv
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Autores principales: Lin, Yi, Liu, Yanfei, Chen, Hao, Yang, Xin, Ma, Kai, Zheng, Yefeng, Cheng, Kwang-Ting
Formato: Preprint
Publicado: 2021
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author Lin, Yi
Liu, Yanfei
Chen, Hao
Yang, Xin
Ma, Kai
Zheng, Yefeng
Cheng, Kwang-Ting
author_facet Lin, Yi
Liu, Yanfei
Chen, Hao
Yang, Xin
Ma, Kai
Zheng, Yefeng
Cheng, Kwang-Ting
contents Radiation therapy treatment planning requires balancing the delivery of the target dose while sparing normal tissues, making it a complex process. To streamline the planning process and enhance its quality, there is a growing demand for knowledge-based planning (KBP). Ensemble learning has shown impressive power in various deep learning tasks, and it has great potential to improve the performance of KBP. However, the effectiveness of ensemble learning heavily depends on the diversity and individual accuracy of the base learners. Moreover, the complexity of model ensembles is a major concern, as it requires maintaining multiple models during inference, leading to increased computational cost and storage overhead. In this study, we propose a novel learning-based ensemble approach named LENAS, which integrates neural architecture search with knowledge distillation for 3D radiotherapy dose prediction. Our approach starts by exhaustively searching each block from an enormous architecture space to identify multiple architectures that exhibit promising performance and significant diversity. To mitigate the complexity introduced by the model ensemble, we adopt the teacher-student paradigm, leveraging the diverse outputs from multiple learned networks as supervisory signals to guide the training of the student network. Furthermore, to preserve high-level semantic information, we design a hybrid-loss to optimize the student network, enabling it to recover the knowledge embedded within the teacher networks. The proposed method has been evaluated on two public datasets, OpenKBP and AIMIS. Extensive experimental results demonstrate the effectiveness of our method and its superior performance to the state-of-the-art methods.
format Preprint
id arxiv_https___arxiv_org_abs_2106_06733
institution arXiv
publishDate 2021
record_format arxiv
spellingShingle LENAS: Learning-based Neural Architecture Search and Ensemble for 3D Radiotherapy Dose Prediction
Lin, Yi
Liu, Yanfei
Chen, Hao
Yang, Xin
Ma, Kai
Zheng, Yefeng
Cheng, Kwang-Ting
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
Radiation therapy treatment planning requires balancing the delivery of the target dose while sparing normal tissues, making it a complex process. To streamline the planning process and enhance its quality, there is a growing demand for knowledge-based planning (KBP). Ensemble learning has shown impressive power in various deep learning tasks, and it has great potential to improve the performance of KBP. However, the effectiveness of ensemble learning heavily depends on the diversity and individual accuracy of the base learners. Moreover, the complexity of model ensembles is a major concern, as it requires maintaining multiple models during inference, leading to increased computational cost and storage overhead. In this study, we propose a novel learning-based ensemble approach named LENAS, which integrates neural architecture search with knowledge distillation for 3D radiotherapy dose prediction. Our approach starts by exhaustively searching each block from an enormous architecture space to identify multiple architectures that exhibit promising performance and significant diversity. To mitigate the complexity introduced by the model ensemble, we adopt the teacher-student paradigm, leveraging the diverse outputs from multiple learned networks as supervisory signals to guide the training of the student network. Furthermore, to preserve high-level semantic information, we design a hybrid-loss to optimize the student network, enabling it to recover the knowledge embedded within the teacher networks. The proposed method has been evaluated on two public datasets, OpenKBP and AIMIS. Extensive experimental results demonstrate the effectiveness of our method and its superior performance to the state-of-the-art methods.
title LENAS: Learning-based Neural Architecture Search and Ensemble for 3D Radiotherapy Dose Prediction
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2106.06733