Causal Inference in Longitudinal Data under Unknown Interference

Fuente: arXiv
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Autori principali: Wang, Ye, Jetsupphasuk, Michael
Natura: Preprint
Pubblicazione: 2021
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author Wang, Ye
Jetsupphasuk, Michael
author_facet Wang, Ye
Jetsupphasuk, Michael
contents In longitudinal studies where units are embedded in space or a social network, interference may arise, meaning that a unit's outcome can depend on treatment histories of others. The presence of interference poses significant challenges for causal inference, particularly when the interference structure -- how a unit's outcome responds to others' influences -- is complex, heterogeneous, and unknown to researchers. This paper develops a general framework for identifying and estimating both direct and spillover effects of treatment histories under minimal assumptions about the interference structure. We introduce a class of causal estimands that capture the effects of treatment histories at any specified proximity level and show that they can be represented by a modified marginal structural model. Under sequential exchangeability, these estimands are identifiable and can be estimated using inverse probability weighting. We derive conditions for consistency and asymptotic normality of the estimators and provide procedures for constructing asymptotically conservative confidence intervals. The method's utility is demonstrated through applications in both social science and biomedical settings.
format Preprint
id arxiv_https___arxiv_org_abs_2106_15074
institution arXiv
publishDate 2021
record_format arxiv
spellingShingle Causal Inference in Longitudinal Data under Unknown Interference
Wang, Ye
Jetsupphasuk, Michael
Methodology
Statistics Theory
Applications
In longitudinal studies where units are embedded in space or a social network, interference may arise, meaning that a unit's outcome can depend on treatment histories of others. The presence of interference poses significant challenges for causal inference, particularly when the interference structure -- how a unit's outcome responds to others' influences -- is complex, heterogeneous, and unknown to researchers. This paper develops a general framework for identifying and estimating both direct and spillover effects of treatment histories under minimal assumptions about the interference structure. We introduce a class of causal estimands that capture the effects of treatment histories at any specified proximity level and show that they can be represented by a modified marginal structural model. Under sequential exchangeability, these estimands are identifiable and can be estimated using inverse probability weighting. We derive conditions for consistency and asymptotic normality of the estimators and provide procedures for constructing asymptotically conservative confidence intervals. The method's utility is demonstrated through applications in both social science and biomedical settings.
title Causal Inference in Longitudinal Data under Unknown Interference
topic Methodology
Statistics Theory
Applications
url https://arxiv.org/abs/2106.15074