Controlling epidemics through optimal allocation of test kits and vaccine doses across networks

Fuente: arXiv
Salvato in:
Dettagli Bibliografici
Autori principali: Xia, Mingtao, Böttcher, Lucas, Chou, Tom
Natura: Preprint
Pubblicazione: 2021
Soggetti:
Accesso online:
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne!!
_version_ 1866911665067393024
author Xia, Mingtao
Böttcher, Lucas
Chou, Tom
author_facet Xia, Mingtao
Böttcher, Lucas
Chou, Tom
contents Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered, and infected individuals, we present a degree-based testing and vaccination model for which we use control-theoretic methods to derive optimal testing and vaccination policies. Within our framework, we find that optimal intervention policies first target high-degree nodes before shifting to lower-degree nodes in a time-dependent manner. Using such optimal policies, it is possible to delay outbreaks and reduce incidence rates to a greater extent than uniform and reinforcement-learning-based interventions, particularly on certain scale-free networks.
format Preprint
id arxiv_https___arxiv_org_abs_2107_13709
institution arXiv
publishDate 2021
record_format arxiv
spellingShingle Controlling epidemics through optimal allocation of test kits and vaccine doses across networks
Xia, Mingtao
Böttcher, Lucas
Chou, Tom
Populations and Evolution
Social and Information Networks
Optimization and Control
Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered, and infected individuals, we present a degree-based testing and vaccination model for which we use control-theoretic methods to derive optimal testing and vaccination policies. Within our framework, we find that optimal intervention policies first target high-degree nodes before shifting to lower-degree nodes in a time-dependent manner. Using such optimal policies, it is possible to delay outbreaks and reduce incidence rates to a greater extent than uniform and reinforcement-learning-based interventions, particularly on certain scale-free networks.
title Controlling epidemics through optimal allocation of test kits and vaccine doses across networks
topic Populations and Evolution
Social and Information Networks
Optimization and Control
url https://arxiv.org/abs/2107.13709