Practical X-ray Gastric Cancer Diagnostic Support Using Refined Stochastic Data Augmentation and Hard Boundary Box Training

Fuente: arXiv
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Auteurs principaux: Okamoto, Hideaki, Cap, Quan Huu, Nomura, Takakiyo, Nabeshima, Kazuhito, Hashimoto, Jun, Iyatomi, Hitoshi
Format: Preprint
Publié: 2021
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author Okamoto, Hideaki
Cap, Quan Huu
Nomura, Takakiyo
Nabeshima, Kazuhito
Hashimoto, Jun
Iyatomi, Hitoshi
author_facet Okamoto, Hideaki
Cap, Quan Huu
Nomura, Takakiyo
Nabeshima, Kazuhito
Hashimoto, Jun
Iyatomi, Hitoshi
contents Endoscopy is widely used to diagnose gastric cancer and has a high diagnostic performance, but it must be performed by a physician, which limits the number of people who can be diagnosed. In contrast, gastric X-rays can be taken by radiographers, thus allowing a much larger number of patients to undergo imaging. However, the diagnosis of X-ray images relies heavily on the expertise and experience of physicians, and few machine learning methods have been developed to assist in this process. We propose a novel and practical gastric cancer diagnostic support system for gastric X-ray images that will enable more people to be screened. The system is based on a general deep learning-based object detection model and incorporates two novel techniques: refined probabilistic stomach image augmentation (R-sGAIA) and hard boundary box training (HBBT). R-sGAIA enhances the probabilistic gastric fold region and provides more learning patterns for cancer detection models. HBBT is an efficient training method that improves model performance by allowing the use of unannotated negative (i.e., healthy control) samples, which are typically unusable in conventional detection models. The proposed system achieved a sensitivity (SE) for gastric cancer of 90.2\%, higher than that of an expert (85.5%). Under these conditions, two out of five candidate boxes identified by the system were cancerous (precision = 42.5%), with an image processing speed of 0.51 seconds per image. The system also outperformed methods using the same object detection model and state-of-the-art data augmentation by showing a 5.9-point improvement in the F1 score. In summary, this system efficiently identifies areas for radiologists to examine within a practical time frame, thus significantly reducing their workload.
format Preprint
id arxiv_https___arxiv_org_abs_2108_08158
institution arXiv
publishDate 2021
record_format arxiv
spellingShingle Practical X-ray Gastric Cancer Diagnostic Support Using Refined Stochastic Data Augmentation and Hard Boundary Box Training
Okamoto, Hideaki
Cap, Quan Huu
Nomura, Takakiyo
Nabeshima, Kazuhito
Hashimoto, Jun
Iyatomi, Hitoshi
Image and Video Processing
Computer Vision and Pattern Recognition
Endoscopy is widely used to diagnose gastric cancer and has a high diagnostic performance, but it must be performed by a physician, which limits the number of people who can be diagnosed. In contrast, gastric X-rays can be taken by radiographers, thus allowing a much larger number of patients to undergo imaging. However, the diagnosis of X-ray images relies heavily on the expertise and experience of physicians, and few machine learning methods have been developed to assist in this process. We propose a novel and practical gastric cancer diagnostic support system for gastric X-ray images that will enable more people to be screened. The system is based on a general deep learning-based object detection model and incorporates two novel techniques: refined probabilistic stomach image augmentation (R-sGAIA) and hard boundary box training (HBBT). R-sGAIA enhances the probabilistic gastric fold region and provides more learning patterns for cancer detection models. HBBT is an efficient training method that improves model performance by allowing the use of unannotated negative (i.e., healthy control) samples, which are typically unusable in conventional detection models. The proposed system achieved a sensitivity (SE) for gastric cancer of 90.2\%, higher than that of an expert (85.5%). Under these conditions, two out of five candidate boxes identified by the system were cancerous (precision = 42.5%), with an image processing speed of 0.51 seconds per image. The system also outperformed methods using the same object detection model and state-of-the-art data augmentation by showing a 5.9-point improvement in the F1 score. In summary, this system efficiently identifies areas for radiologists to examine within a practical time frame, thus significantly reducing their workload.
title Practical X-ray Gastric Cancer Diagnostic Support Using Refined Stochastic Data Augmentation and Hard Boundary Box Training
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2108.08158