Deep DNA Storage: Scalable and Robust DNA Storage via Coding Theory and Deep Learning

Fuente: arXiv
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Auteurs principaux: Bar-Lev, Daniella, Orr, Itai, Sabary, Omer, Etzion, Tuvi, Yaakobi, Eitan
Format: Preprint
Publié: 2021
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author Bar-Lev, Daniella
Orr, Itai
Sabary, Omer
Etzion, Tuvi
Yaakobi, Eitan
author_facet Bar-Lev, Daniella
Orr, Itai
Sabary, Omer
Etzion, Tuvi
Yaakobi, Eitan
contents DNA-based storage is an emerging technology that enables digital information to be archived in DNA molecules. This method enjoys major advantages over magnetic and optical storage solutions such as exceptional information density, enhanced data durability, and negligible power consumption to maintain data integrity. To access the data, an information retrieval process is employed, where some of the main bottlenecks are the scalability and accuracy, which have a natural tradeoff between the two. Here we show a modular and holistic approach that combines Deep Neural Networks (DNN) trained on simulated data, Tensor-Product (TP) based Error-Correcting Codes (ECC), and a safety margin mechanism into a single coherent pipeline. We demonstrated our solution on 3.1MB of information using two different sequencing technologies. Our work improves upon the current leading solutions by up to x3200 increase in speed, 40% improvement in accuracy, and offers a code rate of 1.6 bits per base in a high noise regime. In a broader sense, our work shows a viable path to commercial DNA storage solutions hindered by current information retrieval processes.
format Preprint
id arxiv_https___arxiv_org_abs_2109_00031
institution arXiv
publishDate 2021
record_format arxiv
spellingShingle Deep DNA Storage: Scalable and Robust DNA Storage via Coding Theory and Deep Learning
Bar-Lev, Daniella
Orr, Itai
Sabary, Omer
Etzion, Tuvi
Yaakobi, Eitan
Information Theory
Artificial Intelligence
DNA-based storage is an emerging technology that enables digital information to be archived in DNA molecules. This method enjoys major advantages over magnetic and optical storage solutions such as exceptional information density, enhanced data durability, and negligible power consumption to maintain data integrity. To access the data, an information retrieval process is employed, where some of the main bottlenecks are the scalability and accuracy, which have a natural tradeoff between the two. Here we show a modular and holistic approach that combines Deep Neural Networks (DNN) trained on simulated data, Tensor-Product (TP) based Error-Correcting Codes (ECC), and a safety margin mechanism into a single coherent pipeline. We demonstrated our solution on 3.1MB of information using two different sequencing technologies. Our work improves upon the current leading solutions by up to x3200 increase in speed, 40% improvement in accuracy, and offers a code rate of 1.6 bits per base in a high noise regime. In a broader sense, our work shows a viable path to commercial DNA storage solutions hindered by current information retrieval processes.
title Deep DNA Storage: Scalable and Robust DNA Storage via Coding Theory and Deep Learning
topic Information Theory
Artificial Intelligence
url https://arxiv.org/abs/2109.00031