Mobility and the spatial spread of SARS-CoV-2 in Belgium

Fuente: arXiv
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Autores principales: Rollier, Michiel, Miranda, Gisele H. B., Vergeynst, Jenna, Meys, Joris, Alleman, Tijs W., Surveillance, the Belgian Collaborative Group on COVID-19 Hospital, Baetens, Jan M.
Formato: Preprint
Publicado: 2022
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author Rollier, Michiel
Miranda, Gisele H. B.
Vergeynst, Jenna
Meys, Joris
Alleman, Tijs W.
Surveillance, the Belgian Collaborative Group on COVID-19 Hospital
Baetens, Jan M.
author_facet Rollier, Michiel
Miranda, Gisele H. B.
Vergeynst, Jenna
Meys, Joris
Alleman, Tijs W.
Surveillance, the Belgian Collaborative Group on COVID-19 Hospital
Baetens, Jan M.
contents We analyse and mutually compare time series of COVID-19-related data and mobility data across Belgium's 43 arrondissements (NUTS 3). In this way, we reach three conclusions. First, we could detect a decrease in mobility during high-incidence stages of the pandemic. This is expressed as a significant change in the average amount of time spent outside one's home arrondissement, investigated over five distinct periods, and in more detail using an inter-arrondissement ``connectivity index'' (CI). Second, we analyse spatio-temporal COVID-19-related hospitalisation time series, after smoothing them using a generalise additive mixed model (GAMM). We confirm that some arrondissements are ahead of others and morphologically dissimilar to others, in terms of epidemiological progression. The tools used to quantify this are time-lagged cross-correlation (TLCC) and dynamic time warping (DTW), respectively. Third, we demonstrate that an arrondissement's CI with one of the three identified first-outbreak arrondissements is correlated to a significant local excess mortality some five to six weeks after the first outbreak. More generally, we couple results leading to the first and second conclusion, in order to demonstrate an overall correlation between CI values on the one hand, and TLCC and DTW values on the other. We conclude that there is a strong correlation between physical movement of people and viral spread in the early stage of the SARS-CoV-2 epidemic in Belgium, though its strength weakens as the virus spreads
format Preprint
id arxiv_https___arxiv_org_abs_2202_11528
institution arXiv
publishDate 2022
record_format arxiv
spellingShingle Mobility and the spatial spread of SARS-CoV-2 in Belgium
Rollier, Michiel
Miranda, Gisele H. B.
Vergeynst, Jenna
Meys, Joris
Alleman, Tijs W.
Surveillance, the Belgian Collaborative Group on COVID-19 Hospital
Baetens, Jan M.
Physics and Society
Applications
We analyse and mutually compare time series of COVID-19-related data and mobility data across Belgium's 43 arrondissements (NUTS 3). In this way, we reach three conclusions. First, we could detect a decrease in mobility during high-incidence stages of the pandemic. This is expressed as a significant change in the average amount of time spent outside one's home arrondissement, investigated over five distinct periods, and in more detail using an inter-arrondissement ``connectivity index'' (CI). Second, we analyse spatio-temporal COVID-19-related hospitalisation time series, after smoothing them using a generalise additive mixed model (GAMM). We confirm that some arrondissements are ahead of others and morphologically dissimilar to others, in terms of epidemiological progression. The tools used to quantify this are time-lagged cross-correlation (TLCC) and dynamic time warping (DTW), respectively. Third, we demonstrate that an arrondissement's CI with one of the three identified first-outbreak arrondissements is correlated to a significant local excess mortality some five to six weeks after the first outbreak. More generally, we couple results leading to the first and second conclusion, in order to demonstrate an overall correlation between CI values on the one hand, and TLCC and DTW values on the other. We conclude that there is a strong correlation between physical movement of people and viral spread in the early stage of the SARS-CoV-2 epidemic in Belgium, though its strength weakens as the virus spreads
title Mobility and the spatial spread of SARS-CoV-2 in Belgium
topic Physics and Society
Applications
url https://arxiv.org/abs/2202.11528