New-Onset Diabetes Assessment Using Artificial Intelligence-Enhanced Electrocardiography

Fuente: arXiv
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Autori principali: Zhang, Hao, Jethani, Neil, Puli, Aahlad, Garber, Leonid, Jankelson, Lior, Aphinyanaphongs, Yindalon, Ranganath, Rajesh
Natura: Preprint
Pubblicazione: 2022
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author Zhang, Hao
Jethani, Neil
Puli, Aahlad
Garber, Leonid
Jankelson, Lior
Aphinyanaphongs, Yindalon
Ranganath, Rajesh
author_facet Zhang, Hao
Jethani, Neil
Puli, Aahlad
Garber, Leonid
Jankelson, Lior
Aphinyanaphongs, Yindalon
Ranganath, Rajesh
contents Diabetes has a long asymptomatic period which can often remain undiagnosed for multiple years. In this study, we trained a deep learning model to detect new-onset diabetes using 12-lead ECG and readily available demographic information. To do so, we used retrospective data where patients have both a hemoglobin A1c and ECG measured. However, such patients may not be representative of the complete patient population. As part of the study, we proposed a methodology to evaluate our model in the target population by estimating the probability of receiving an A1c test and reweight the retrospective population to represent the general population. We also adapted an efficient algorithm to generate Shapley values for both ECG signals and demographic features at the same time for model interpretation. The model offers an automated, more accurate method for early diabetes detection compared to current screening efforts. Their potential use in wearable devices can facilitate large-scale, community-wide screening, improving healthcare outcomes.
format Preprint
id arxiv_https___arxiv_org_abs_2205_02900
institution arXiv
publishDate 2022
record_format arxiv
spellingShingle New-Onset Diabetes Assessment Using Artificial Intelligence-Enhanced Electrocardiography
Zhang, Hao
Jethani, Neil
Puli, Aahlad
Garber, Leonid
Jankelson, Lior
Aphinyanaphongs, Yindalon
Ranganath, Rajesh
Machine Learning
Artificial Intelligence
Computers and Society
Diabetes has a long asymptomatic period which can often remain undiagnosed for multiple years. In this study, we trained a deep learning model to detect new-onset diabetes using 12-lead ECG and readily available demographic information. To do so, we used retrospective data where patients have both a hemoglobin A1c and ECG measured. However, such patients may not be representative of the complete patient population. As part of the study, we proposed a methodology to evaluate our model in the target population by estimating the probability of receiving an A1c test and reweight the retrospective population to represent the general population. We also adapted an efficient algorithm to generate Shapley values for both ECG signals and demographic features at the same time for model interpretation. The model offers an automated, more accurate method for early diabetes detection compared to current screening efforts. Their potential use in wearable devices can facilitate large-scale, community-wide screening, improving healthcare outcomes.
title New-Onset Diabetes Assessment Using Artificial Intelligence-Enhanced Electrocardiography
topic Machine Learning
Artificial Intelligence
Computers and Society
url https://arxiv.org/abs/2205.02900