Choice of training label matters: how to best use deep learning for quantitative MRI parameter estimation

Fuente: arXiv
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Autores principales: Epstein, Sean C., Bray, Timothy J. P., Hall-Craggs, Margaret, Zhang, Hui
Formato: Preprint
Publicado: 2022
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author Epstein, Sean C.
Bray, Timothy J. P.
Hall-Craggs, Margaret
Zhang, Hui
author_facet Epstein, Sean C.
Bray, Timothy J. P.
Hall-Craggs, Margaret
Zhang, Hui
contents Deep learning (DL) is gaining popularity as a parameter estimation method for quantitative MRI. A range of competing implementations have been proposed, relying on either supervised or self-supervised learning. Self-supervised approaches, sometimes referred to as unsupervised, have been loosely based on auto-encoders, whereas supervised methods have, to date, been trained on groundtruth labels. These two learning paradigms have been shown to have distinct strengths. Notably, self-supervised approaches have offered lower-bias parameter estimates than their supervised alternatives. This result is counterintuitive - incorporating prior knowledge with supervised labels should, in theory, lead to improved accuracy. In this work, we show that this apparent limitation of supervised approaches stems from the naive choice of groundtruth training labels. By training on labels which are deliberately not groundtruth, we show that the low-bias parameter estimation previously associated with self-supervised methods can be replicated - and improved on - within a supervised learning framework. This approach sets the stage for a single, unifying, deep learning parameter estimation framework, based on supervised learning, where trade-offs between bias and variance are made by careful adjustment of training label.
format Preprint
id arxiv_https___arxiv_org_abs_2205_05587
institution arXiv
publishDate 2022
record_format arxiv
spellingShingle Choice of training label matters: how to best use deep learning for quantitative MRI parameter estimation
Epstein, Sean C.
Bray, Timothy J. P.
Hall-Craggs, Margaret
Zhang, Hui
Medical Physics
Machine Learning
Image and Video Processing
Deep learning (DL) is gaining popularity as a parameter estimation method for quantitative MRI. A range of competing implementations have been proposed, relying on either supervised or self-supervised learning. Self-supervised approaches, sometimes referred to as unsupervised, have been loosely based on auto-encoders, whereas supervised methods have, to date, been trained on groundtruth labels. These two learning paradigms have been shown to have distinct strengths. Notably, self-supervised approaches have offered lower-bias parameter estimates than their supervised alternatives. This result is counterintuitive - incorporating prior knowledge with supervised labels should, in theory, lead to improved accuracy. In this work, we show that this apparent limitation of supervised approaches stems from the naive choice of groundtruth training labels. By training on labels which are deliberately not groundtruth, we show that the low-bias parameter estimation previously associated with self-supervised methods can be replicated - and improved on - within a supervised learning framework. This approach sets the stage for a single, unifying, deep learning parameter estimation framework, based on supervised learning, where trade-offs between bias and variance are made by careful adjustment of training label.
title Choice of training label matters: how to best use deep learning for quantitative MRI parameter estimation
topic Medical Physics
Machine Learning
Image and Video Processing
url https://arxiv.org/abs/2205.05587