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Bibliographic Details
Main Authors: Riabenko, I., Prokhorenko, S., Klimova, E., Beloshenko, K.
Format: Preprint
Published: 2022
Subjects:
Online Access:https://arxiv.org/abs/2208.02014
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Table of Contents:
  • This study investigates the application of surface-enhanced Raman spectroscopy (SERS) as a diagnostic tool for myasthenia gravis, a severe neuromuscular disorder characterized by muscle weakness and fatigue. Blood serum samples were analyzed using SERS substrates embedded with 5 nm gold nanoparticles, resulting in significant Raman signal enhancement and the detection of disease-specific spectral features. The study demonstrates the potential of SERS to identify subtle biochemical changes associated with oxidative stress and altered molecular composition in serum, providing a sensitive and non-invasive approach for diagnosis.