Causal inference in drug discovery and development

Fuente: arXiv
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Hauptverfasser: Michoel, Tom, Zhang, Jitao David
Format: Preprint
Veröffentlicht: 2022
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author Michoel, Tom
Zhang, Jitao David
author_facet Michoel, Tom
Zhang, Jitao David
contents To discover new drugs is to seek and to prove causality. As an emerging approach leveraging human knowledge and creativity, data, and machine intelligence, causal inference holds the promise of reducing cognitive bias and improving decision making in drug discovery. While it has been applied across the value chain, the concepts and practice of causal inference remain obscure to many practitioners. This article offers a non-technical introduction to causal inference, reviews its recent applications, and discusses opportunities and challenges of adopting the causal language in drug discovery and development.
format Preprint
id arxiv_https___arxiv_org_abs_2209_14664
institution arXiv
publishDate 2022
record_format arxiv
spellingShingle Causal inference in drug discovery and development
Michoel, Tom
Zhang, Jitao David
Quantitative Methods
Machine Learning
Applications
To discover new drugs is to seek and to prove causality. As an emerging approach leveraging human knowledge and creativity, data, and machine intelligence, causal inference holds the promise of reducing cognitive bias and improving decision making in drug discovery. While it has been applied across the value chain, the concepts and practice of causal inference remain obscure to many practitioners. This article offers a non-technical introduction to causal inference, reviews its recent applications, and discusses opportunities and challenges of adopting the causal language in drug discovery and development.
title Causal inference in drug discovery and development
topic Quantitative Methods
Machine Learning
Applications
url https://arxiv.org/abs/2209.14664