Cover Image

Designing an exploratory phase 2b platform trial in NASH with correlated, co-primary binary endpoints

Fuente: arXiv

Saved in:

Bibliographic Details
Main Authors:	Meyer, Elias Laurin, Mesenbrink, Peter, Di Prospero, Nicholas A., Pericàs, Juan M., Glimm, Ekkehard, Ratziu, Vlad, Sena, Elena, König, Franz
Format:	Preprint
Published:	2022
Subjects:	Applications
Online Access:	Acceder al recurso
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Exact matching as an alternative to propensity score matching
by: Glimm, Ekkehard, et al.
Published: (2025)

A novel longitudinal rank-sum test for multiple primary endpoints in clinical trials: Applications to neurodegenerative disorders
by: Xu, Xiaoming, et al.
Published: (2024)

Futility Analysis under Scrutiny
by: Jin, Rui, et al.
Published: (2025)

Optimal allocation strategies in platform trials
by: Roig, Marta Bofill, et al.
Published: (2023)

Rank-based estimators of global treatment effects for cluster randomized trials with multiple endpoints
by: Smith, E. Davies, et al.
Published: (2024)

Evaluating amyloid-beta as a surrogate endpoint in trials of anti-amyloid drugs in Alzheimer's disease: a Bayesian meta-analysis
by: Ren, Sa, et al.
Published: (2025)

A comparison of methods for designing hybrid type 2 cluster-randomized trials with continuous effectiveness and implementation endpoints
by: Owen, Melody, et al.
Published: (2025)

While-alive regression analysis of composite survival endpoints
by: Fang, Xi, et al.
Published: (2025)

NCC: An R-package for analysis and simulation of platform trials with non-concurrent controls
by: Krotka, Pavla, et al.
Published: (2023)

Using shrinkage methods to estimate treatment effects in overlapping subgroups in randomized clinical trials with a time-to-event endpoint
by: Wolbers, Marcel, et al.
Published: (2024)

Prediction intervals for overdispersed binomial endpoints and their application to toxicological historical control data
by: Menssen, Max, et al.
Published: (2024)

Visualizing the treatment effect on kidney hierarchical composite endpoints: From mosaic to maraca plots
by: Karpefors, Martin, et al.
Published: (2025)

Microbial correlation: a semi-parametric model for investigating microbial co-metabolism
by: Shi, Haoran, et al.
Published: (2025)

Optimal allocation of trials to sub-regions in crop variety testing with multiple years and correlated genotype effects
by: Prus, Maryna, et al.
Published: (2026)

Use of surrogate endpoints in health technology assessment: a review of selected NICE technology appraisals in oncology
by: Wheaton, Lorna, et al.
Published: (2024)

Nonparametric estimation of an optimal treatment rule with fused randomized trials and missing effect modifiers
by: Williams, Nicholas, et al.
Published: (2025)

Assessing treatment efficacy for interval-censored endpoints using multistate semi-Markov models fit to multiple data streams
by: Morsomme, Raphael, et al.
Published: (2025)

The role of randomization inference in unraveling individual treatment effects in early phase vaccine trials
by: Chen, Zhe, et al.
Published: (2023)

Cristiano Ronaldo or Lionel Messi, who is more consistent in scoring goals? The evidence from CFM exploratory analysis
by: Anwar, Samsul, et al.
Published: (2026)

A response-adaptive multi-arm design for continuous endpoints based on a weighted information measure
by: Caruso, Gianmarco, et al.
Published: (2024)

Scaling behavioral incentives for low-carbon mobility through digital platforms
by: Liu, Bing, et al.
Published: (2025)

Shared Keyboard: An improved Bayesian design for phase I clinical trials via Beta kernel process
by: Zhao, Jiangyan, et al.
Published: (2026)

Mosqlimate: a platform to providing automatable access to data and forecasting models for arbovirus disease
by: Ganem, Fabiana, et al.
Published: (2024)

Equipoise calibration of clinical trial design
by: Rigat, Fabio
Published: (2025)

Uncovering migration systems through spatio-temporal tensor co-clustering
by: Almquist, Zack W., et al.
Published: (2021)

Early developmental carry‐over effects on exploratory behaviour and DNA methylation in wild great tits (Parus major)
by: Bernice Sepers, et al.
Published: (2024)

Model-based indicators for co-clustered environments and species communities
by: Scherting, Braden, et al.
Published: (2025)

Shotgun DNA sequencing evidence: sample-specific and unknown genotyping error probabilities
by: Andersen, Mikkel Meyer
Published: (2025)

On misconceptions about the Brier score in binary prediction models
by: Hoessly, Linard
Published: (2025)

Evaluation of clinical utility in emulated clinical trials
by: Hruza, Johannes, et al.
Published: (2025)

Incorporating estimands into meta-analyses of clinical trials
by: Remiro-Azócar, Antonio, et al.
Published: (2025)

tsbootstrap: Enhancing Time Series Analysis with Advanced Bootstrapping Techniques
by: Gilda, Sankalp, et al.
Published: (2024)

Yield forecasting based on short time series with high spatial resolution data
by: Pokal, Sayli, et al.
Published: (2024)

The Bayesian optimal two-stage design for clinical phase II trials based on Bayes factors
by: Kelter, Riko, et al.
Published: (2025)

Monitoring overall survival in pivotal trials in indolent cancers
by: Fleming, Thomas R, et al.
Published: (2023)

Benchmarking covariate-adjustment strategies for randomized clinical trials
by: Shao, Yulin, et al.
Published: (2026)

Mixed additive modelling of global alien species co-invasions of plants and insects
by: Boschi, Martina, et al.
Published: (2023)

Generalizing conditional average treatment effects from nested randomized trials to all trial-eligible individuals
by: Wen, Lan, et al.
Published: (2026)

Negative correlations in Ising models of credit risk
by: Emonti, Chiara, et al.
Published: (2025)

Clinical trials with interim analyses: Standardizing Terminology to increase clarity
by: Asikanius, Elina, et al.
Published: (2024)