Generation of Anonymous Chest Radiographs Using Latent Diffusion Models for Training Thoracic Abnormality Classification Systems

Fuente: arXiv
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Autori principali: Packhäuser, Kai, Folle, Lukas, Thamm, Florian, Maier, Andreas
Natura: Preprint
Pubblicazione: 2022
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author Packhäuser, Kai
Folle, Lukas
Thamm, Florian
Maier, Andreas
author_facet Packhäuser, Kai
Folle, Lukas
Thamm, Florian
Maier, Andreas
contents The availability of large-scale chest X-ray datasets is a requirement for developing well-performing deep learning-based algorithms in thoracic abnormality detection and classification. However, biometric identifiers in chest radiographs hinder the public sharing of such data for research purposes due to the risk of patient re-identification. To counteract this issue, synthetic data generation offers a solution for anonymizing medical images. This work employs a latent diffusion model to synthesize an anonymous chest X-ray dataset of high-quality class-conditional images. We propose a privacy-enhancing sampling strategy to ensure the non-transference of biometric information during the image generation process. The quality of the generated images and the feasibility of serving as exclusive training data are evaluated on a thoracic abnormality classification task. Compared to a real classifier, we achieve competitive results with a performance gap of only 3.5% in the area under the receiver operating characteristic curve.
format Preprint
id arxiv_https___arxiv_org_abs_2211_01323
institution arXiv
publishDate 2022
record_format arxiv
spellingShingle Generation of Anonymous Chest Radiographs Using Latent Diffusion Models for Training Thoracic Abnormality Classification Systems
Packhäuser, Kai
Folle, Lukas
Thamm, Florian
Maier, Andreas
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
The availability of large-scale chest X-ray datasets is a requirement for developing well-performing deep learning-based algorithms in thoracic abnormality detection and classification. However, biometric identifiers in chest radiographs hinder the public sharing of such data for research purposes due to the risk of patient re-identification. To counteract this issue, synthetic data generation offers a solution for anonymizing medical images. This work employs a latent diffusion model to synthesize an anonymous chest X-ray dataset of high-quality class-conditional images. We propose a privacy-enhancing sampling strategy to ensure the non-transference of biometric information during the image generation process. The quality of the generated images and the feasibility of serving as exclusive training data are evaluated on a thoracic abnormality classification task. Compared to a real classifier, we achieve competitive results with a performance gap of only 3.5% in the area under the receiver operating characteristic curve.
title Generation of Anonymous Chest Radiographs Using Latent Diffusion Models for Training Thoracic Abnormality Classification Systems
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2211.01323