Improving Uncertainty-based Out-of-Distribution Detection for Medical Image Segmentation

Fuente: arXiv
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Main Authors: Lambert, Benjamin, Forbes, Florence, Doyle, Senan, Tucholka, Alan, Dojat, Michel
Format: Preprint
Published: 2022
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author Lambert, Benjamin
Forbes, Florence
Doyle, Senan
Tucholka, Alan
Dojat, Michel
author_facet Lambert, Benjamin
Forbes, Florence
Doyle, Senan
Tucholka, Alan
Dojat, Michel
contents Deep Learning models are easily disturbed by variations in the input images that were not seen during training, resulting in unpredictable behaviours. Such Out-of-Distribution (OOD) images represent a significant challenge in the context of medical image analysis, where the range of possible abnormalities is extremely wide, including artifacts, unseen pathologies, or different imaging protocols. In this work, we evaluate various uncertainty frameworks to detect OOD inputs in the context of Multiple Sclerosis lesions segmentation. By implementing a comprehensive evaluation scheme including 14 sources of OOD of various nature and strength, we show that methods relying on the predictive uncertainty of binary segmentation models often fails in detecting outlying inputs. On the contrary, learning to segment anatomical labels alongside lesions highly improves the ability to detect OOD inputs.
format Preprint
id arxiv_https___arxiv_org_abs_2211_05421
institution arXiv
publishDate 2022
record_format arxiv
spellingShingle Improving Uncertainty-based Out-of-Distribution Detection for Medical Image Segmentation
Lambert, Benjamin
Forbes, Florence
Doyle, Senan
Tucholka, Alan
Dojat, Michel
Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
Deep Learning models are easily disturbed by variations in the input images that were not seen during training, resulting in unpredictable behaviours. Such Out-of-Distribution (OOD) images represent a significant challenge in the context of medical image analysis, where the range of possible abnormalities is extremely wide, including artifacts, unseen pathologies, or different imaging protocols. In this work, we evaluate various uncertainty frameworks to detect OOD inputs in the context of Multiple Sclerosis lesions segmentation. By implementing a comprehensive evaluation scheme including 14 sources of OOD of various nature and strength, we show that methods relying on the predictive uncertainty of binary segmentation models often fails in detecting outlying inputs. On the contrary, learning to segment anatomical labels alongside lesions highly improves the ability to detect OOD inputs.
title Improving Uncertainty-based Out-of-Distribution Detection for Medical Image Segmentation
topic Image and Video Processing
Computer Vision and Pattern Recognition
Machine Learning
url https://arxiv.org/abs/2211.05421