InstantGroup: Instant Template Generation for Scalable Group of Brain MRI Registration

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Hauptverfasser: He, Ziyi, Chung, Albert C. S.
Format: Preprint
Veröffentlicht: 2022
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author He, Ziyi
Chung, Albert C. S.
author_facet He, Ziyi
Chung, Albert C. S.
contents Template generation is a critical step in groupwise image registration, which involves aligning a group of subjects into a common space. While existing methods can generate high-quality template images, they often incur substantial time costs or are limited by fixed group scales. In this paper, we present InstantGroup, an efficient groupwise template generation framework based on variational autoencoder (VAE) models that leverage latent representations' arithmetic properties, enabling scalability to groups of any size. InstantGroup features a Dual VAE backbone with shared-weight twin networks to handle pairs of inputs and incorporates a Displacement Inversion Module (DIM) to maintain template unbiasedness and a Subject-Template Alignment Module (STAM) to improve template quality and registration accuracy. Experiments on 3D brain MRI scans from the OASIS and ADNI datasets reveal that InstantGroup dramatically reduces runtime, generating templates within seconds for various group sizes while maintaining superior performance compared to state-of-the-art baselines on quantitative metrics, including unbiasedness and registration accuracy.
format Preprint
id arxiv_https___arxiv_org_abs_2211_05622
institution arXiv
publishDate 2022
record_format arxiv
spellingShingle InstantGroup: Instant Template Generation for Scalable Group of Brain MRI Registration
He, Ziyi
Chung, Albert C. S.
Image and Video Processing
Computer Vision and Pattern Recognition
Template generation is a critical step in groupwise image registration, which involves aligning a group of subjects into a common space. While existing methods can generate high-quality template images, they often incur substantial time costs or are limited by fixed group scales. In this paper, we present InstantGroup, an efficient groupwise template generation framework based on variational autoencoder (VAE) models that leverage latent representations' arithmetic properties, enabling scalability to groups of any size. InstantGroup features a Dual VAE backbone with shared-weight twin networks to handle pairs of inputs and incorporates a Displacement Inversion Module (DIM) to maintain template unbiasedness and a Subject-Template Alignment Module (STAM) to improve template quality and registration accuracy. Experiments on 3D brain MRI scans from the OASIS and ADNI datasets reveal that InstantGroup dramatically reduces runtime, generating templates within seconds for various group sizes while maintaining superior performance compared to state-of-the-art baselines on quantitative metrics, including unbiasedness and registration accuracy.
title InstantGroup: Instant Template Generation for Scalable Group of Brain MRI Registration
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2211.05622