Learning biological neuronal networks with artificial neural networks: neural oscillations

Fuente: arXiv
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Hauptverfasser: Zhang, Ruilin, Wang, Zhongyi, Wu, Tianyi, Cai, Yuhang, Tao, Louis, Xiao, Zhuo-Cheng, Li, Yao
Format: Preprint
Veröffentlicht: 2022
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author Zhang, Ruilin
Wang, Zhongyi
Wu, Tianyi
Cai, Yuhang
Tao, Louis
Xiao, Zhuo-Cheng
Li, Yao
author_facet Zhang, Ruilin
Wang, Zhongyi
Wu, Tianyi
Cai, Yuhang
Tao, Louis
Xiao, Zhuo-Cheng
Li, Yao
contents First-principles-based modelings have been extremely successful in providing crucial insights and predictions for complex biological functions and phenomena. However, they can be hard to build and expensive to simulate for complex living systems. On the other hand, modern data-driven methods thrive at modeling many types of high-dimensional and noisy data. Still, the training and interpretation of these data-driven models remain challenging. Here, we combine the two types of methods to model stochastic neuronal network oscillations. Specifically, we develop a class of first-principles-based artificial neural networks to provide faithful surrogates to the high-dimensional, nonlinear oscillatory dynamics produced by neural circuits in the brain. Furthermore, when the training data set is enlarged within a range of parameter choices, the artificial neural networks become generalizable to these parameters, covering cases in distinctly different dynamical regimes. In all, our work opens a new avenue for modeling complex neuronal network dynamics with artificial neural networks.
format Preprint
id arxiv_https___arxiv_org_abs_2211_11169
institution arXiv
publishDate 2022
record_format arxiv
spellingShingle Learning biological neuronal networks with artificial neural networks: neural oscillations
Zhang, Ruilin
Wang, Zhongyi
Wu, Tianyi
Cai, Yuhang
Tao, Louis
Xiao, Zhuo-Cheng
Li, Yao
Adaptation and Self-Organizing Systems
Neurons and Cognition
First-principles-based modelings have been extremely successful in providing crucial insights and predictions for complex biological functions and phenomena. However, they can be hard to build and expensive to simulate for complex living systems. On the other hand, modern data-driven methods thrive at modeling many types of high-dimensional and noisy data. Still, the training and interpretation of these data-driven models remain challenging. Here, we combine the two types of methods to model stochastic neuronal network oscillations. Specifically, we develop a class of first-principles-based artificial neural networks to provide faithful surrogates to the high-dimensional, nonlinear oscillatory dynamics produced by neural circuits in the brain. Furthermore, when the training data set is enlarged within a range of parameter choices, the artificial neural networks become generalizable to these parameters, covering cases in distinctly different dynamical regimes. In all, our work opens a new avenue for modeling complex neuronal network dynamics with artificial neural networks.
title Learning biological neuronal networks with artificial neural networks: neural oscillations
topic Adaptation and Self-Organizing Systems
Neurons and Cognition
url https://arxiv.org/abs/2211.11169