Bayesian analysis of diffusion-driven multi-type epidemic models with application to COVID-19

Fuente: arXiv
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Autori principali: Bouranis, Lampros, Demiris, Nikolaos, Kalogeropoulos, Konstantinos, Ntzoufras, Ioannis
Natura: Preprint
Pubblicazione: 2022
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author Bouranis, Lampros
Demiris, Nikolaos
Kalogeropoulos, Konstantinos
Ntzoufras, Ioannis
author_facet Bouranis, Lampros
Demiris, Nikolaos
Kalogeropoulos, Konstantinos
Ntzoufras, Ioannis
contents We consider a flexible Bayesian evidence synthesis approach to model the age-specific transmission dynamics of COVID-19 based on daily mortality counts. The temporal evolution of transmission rates in populations containing multiple types of individuals is reconstructed via an appropriate dimension-reduction formulation driven by independent diffusion processes. A suitably tailored compartmental model is used to learn the latent counts of infection, accounting for fluctuations in transmission influenced by public health interventions and changes in human behaviour. The model is fitted to freely available COVID-19 data sources from the UK, Greece, and Austria and validated using a large-scale prevalence survey in England. In particular, we demonstrate how model expansion can facilitate evidence reconciliation at a latent level. The code implementing this work is made freely available via the Bernadette R package.
format Preprint
id arxiv_https___arxiv_org_abs_2211_15229
institution arXiv
publishDate 2022
record_format arxiv
spellingShingle Bayesian analysis of diffusion-driven multi-type epidemic models with application to COVID-19
Bouranis, Lampros
Demiris, Nikolaos
Kalogeropoulos, Konstantinos
Ntzoufras, Ioannis
Computation
Physics and Society
Populations and Evolution
Applications
We consider a flexible Bayesian evidence synthesis approach to model the age-specific transmission dynamics of COVID-19 based on daily mortality counts. The temporal evolution of transmission rates in populations containing multiple types of individuals is reconstructed via an appropriate dimension-reduction formulation driven by independent diffusion processes. A suitably tailored compartmental model is used to learn the latent counts of infection, accounting for fluctuations in transmission influenced by public health interventions and changes in human behaviour. The model is fitted to freely available COVID-19 data sources from the UK, Greece, and Austria and validated using a large-scale prevalence survey in England. In particular, we demonstrate how model expansion can facilitate evidence reconciliation at a latent level. The code implementing this work is made freely available via the Bernadette R package.
title Bayesian analysis of diffusion-driven multi-type epidemic models with application to COVID-19
topic Computation
Physics and Society
Populations and Evolution
Applications
url https://arxiv.org/abs/2211.15229