Early prediction of the risk of ICU mortality with Deep Federated Learning

Fuente: arXiv
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Main Authors: Randl, Korbinian, Armengol, Núria Lladós, Mondrejevski, Lena, Miliou, Ioanna
Format: Preprint
Published: 2022
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author Randl, Korbinian
Armengol, Núria Lladós
Mondrejevski, Lena
Miliou, Ioanna
author_facet Randl, Korbinian
Armengol, Núria Lladós
Mondrejevski, Lena
Miliou, Ioanna
contents Intensive Care Units usually carry patients with a serious risk of mortality. Recent research has shown the ability of Machine Learning to indicate the patients' mortality risk and point physicians toward individuals with a heightened need for care. Nevertheless, healthcare data is often subject to privacy regulations and can therefore not be easily shared in order to build Centralized Machine Learning models that use the combined data of multiple hospitals. Federated Learning is a Machine Learning framework designed for data privacy that can be used to circumvent this problem. In this study, we evaluate the ability of deep Federated Learning to predict the risk of Intensive Care Unit mortality at an early stage. We compare the predictive performance of Federated, Centralized, and Local Machine Learning in terms of AUPRC, F1-score, and AUROC. Our results show that Federated Learning performs equally well as the centralized approach and is substantially better than the local approach, thus providing a viable solution for early Intensive Care Unit mortality prediction. In addition, we show that the prediction performance is higher when the patient history window is closer to discharge or death. Finally, we show that using the F1-score as an early stopping metric can stabilize and increase the performance of our approach for the task at hand.
format Preprint
id arxiv_https___arxiv_org_abs_2212_00554
institution arXiv
publishDate 2022
record_format arxiv
spellingShingle Early prediction of the risk of ICU mortality with Deep Federated Learning
Randl, Korbinian
Armengol, Núria Lladós
Mondrejevski, Lena
Miliou, Ioanna
Machine Learning
Artificial Intelligence
Intensive Care Units usually carry patients with a serious risk of mortality. Recent research has shown the ability of Machine Learning to indicate the patients' mortality risk and point physicians toward individuals with a heightened need for care. Nevertheless, healthcare data is often subject to privacy regulations and can therefore not be easily shared in order to build Centralized Machine Learning models that use the combined data of multiple hospitals. Federated Learning is a Machine Learning framework designed for data privacy that can be used to circumvent this problem. In this study, we evaluate the ability of deep Federated Learning to predict the risk of Intensive Care Unit mortality at an early stage. We compare the predictive performance of Federated, Centralized, and Local Machine Learning in terms of AUPRC, F1-score, and AUROC. Our results show that Federated Learning performs equally well as the centralized approach and is substantially better than the local approach, thus providing a viable solution for early Intensive Care Unit mortality prediction. In addition, we show that the prediction performance is higher when the patient history window is closer to discharge or death. Finally, we show that using the F1-score as an early stopping metric can stabilize and increase the performance of our approach for the task at hand.
title Early prediction of the risk of ICU mortality with Deep Federated Learning
topic Machine Learning
Artificial Intelligence
url https://arxiv.org/abs/2212.00554