Valuing Pharmaceutical Drug Innovations

Fuente: arXiv
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Autori principali: Aryal, Gaurab, Ciliberto, Federico, Farmer, Leland E., Khmelnitskaya, Ekaterina
Natura: Preprint
Pubblicazione: 2022
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author Aryal, Gaurab
Ciliberto, Federico
Farmer, Leland E.
Khmelnitskaya, Ekaterina
author_facet Aryal, Gaurab
Ciliberto, Federico
Farmer, Leland E.
Khmelnitskaya, Ekaterina
contents We propose a methodology to estimate the market value of pharmaceutical drugs. Our approach combines the event study method with a discounted cash flow model that infers drug values from stock market responses to drug development announcements. We estimate the average value of a drug developed by small firms (those below the 95th percentile of market capitalization) to be \$2.16 billion. At the preclinical stage, the risk-adjusted and present discounted average net value of drugs is \$50 million. Leveraging these estimates, we also determine the expected drug development cost at the start of the discovery stage to be \$38 million. We estimate values and costs for several therapeutic areas (e.g., neoplasm, infections) and explore applying these estimates to design policies that support drug development through drug buyouts and targeted preclinical interventions.
format Preprint
id arxiv_https___arxiv_org_abs_2212_07384
institution arXiv
publishDate 2022
record_format arxiv
spellingShingle Valuing Pharmaceutical Drug Innovations
Aryal, Gaurab
Ciliberto, Federico
Farmer, Leland E.
Khmelnitskaya, Ekaterina
General Economics
Economics
We propose a methodology to estimate the market value of pharmaceutical drugs. Our approach combines the event study method with a discounted cash flow model that infers drug values from stock market responses to drug development announcements. We estimate the average value of a drug developed by small firms (those below the 95th percentile of market capitalization) to be \$2.16 billion. At the preclinical stage, the risk-adjusted and present discounted average net value of drugs is \$50 million. Leveraging these estimates, we also determine the expected drug development cost at the start of the discovery stage to be \$38 million. We estimate values and costs for several therapeutic areas (e.g., neoplasm, infections) and explore applying these estimates to design policies that support drug development through drug buyouts and targeted preclinical interventions.
title Valuing Pharmaceutical Drug Innovations
topic General Economics
Economics
url https://arxiv.org/abs/2212.07384