Towards Reliable Medical Image Segmentation by Modeling Evidential Calibrated Uncertainty

Fuente: arXiv
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Auteurs principaux: Zou, Ke, Chen, Yidi, Huang, Ling, Yuan, Xuedong, Shen, Xiaojing, Wang, Meng, Goh, Rick Siow Mong, Liu, Yong, Fu, Huazhu
Format: Preprint
Publié: 2023
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author Zou, Ke
Chen, Yidi
Huang, Ling
Yuan, Xuedong
Shen, Xiaojing
Wang, Meng
Goh, Rick Siow Mong
Liu, Yong
Fu, Huazhu
author_facet Zou, Ke
Chen, Yidi
Huang, Ling
Yuan, Xuedong
Shen, Xiaojing
Wang, Meng
Goh, Rick Siow Mong
Liu, Yong
Fu, Huazhu
contents Medical image segmentation is critical for disease diagnosis and treatment assessment. However, concerns regarding the reliability of segmentation regions persist among clinicians, mainly attributed to the absence of confidence assessment, robustness, and calibration to accuracy. To address this, we introduce DEviS, an easily implementable foundational model that seamlessly integrates into various medical image segmentation networks. DEviS not only enhances the calibration and robustness of baseline segmentation accuracy but also provides high-efficiency uncertainty estimation for reliable predictions. By leveraging subjective logic theory, we explicitly model probability and uncertainty for medical image segmentation. Here, the Dirichlet distribution parameterizes the distribution of probabilities for different classes of the segmentation results. To generate calibrated predictions and uncertainty, we develop a trainable calibrated uncertainty penalty. Furthermore, DEviS incorporates an uncertainty-aware filtering module, which designs the metric of uncertainty-calibrated error to filter out-of-distribution data. We conducted validation studies on publicly available datasets, including ISIC2018, KiTS2021, LiTS2017, and BraTS2019, to assess the accuracy and robustness of different backbone segmentation models enhanced by DEviS, as well as the efficiency and reliability of uncertainty estimation.
format Preprint
id arxiv_https___arxiv_org_abs_2301_00349
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Towards Reliable Medical Image Segmentation by Modeling Evidential Calibrated Uncertainty
Zou, Ke
Chen, Yidi
Huang, Ling
Yuan, Xuedong
Shen, Xiaojing
Wang, Meng
Goh, Rick Siow Mong
Liu, Yong
Fu, Huazhu
Image and Video Processing
Computer Vision and Pattern Recognition
Medical image segmentation is critical for disease diagnosis and treatment assessment. However, concerns regarding the reliability of segmentation regions persist among clinicians, mainly attributed to the absence of confidence assessment, robustness, and calibration to accuracy. To address this, we introduce DEviS, an easily implementable foundational model that seamlessly integrates into various medical image segmentation networks. DEviS not only enhances the calibration and robustness of baseline segmentation accuracy but also provides high-efficiency uncertainty estimation for reliable predictions. By leveraging subjective logic theory, we explicitly model probability and uncertainty for medical image segmentation. Here, the Dirichlet distribution parameterizes the distribution of probabilities for different classes of the segmentation results. To generate calibrated predictions and uncertainty, we develop a trainable calibrated uncertainty penalty. Furthermore, DEviS incorporates an uncertainty-aware filtering module, which designs the metric of uncertainty-calibrated error to filter out-of-distribution data. We conducted validation studies on publicly available datasets, including ISIC2018, KiTS2021, LiTS2017, and BraTS2019, to assess the accuracy and robustness of different backbone segmentation models enhanced by DEviS, as well as the efficiency and reliability of uncertainty estimation.
title Towards Reliable Medical Image Segmentation by Modeling Evidential Calibrated Uncertainty
topic Image and Video Processing
Computer Vision and Pattern Recognition
url https://arxiv.org/abs/2301.00349