SIR-Model for Households

Fuente: arXiv
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Autores principales: Doenges, Philipp, Götz, Thomas, Krueger, Tyll, Niedzielewski, Karol, Priesemann, Viola, Schaefer, Moritz
Formato: Preprint
Publicado: 2023
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author Doenges, Philipp
Götz, Thomas
Krueger, Tyll
Niedzielewski, Karol
Priesemann, Viola
Schaefer, Moritz
author_facet Doenges, Philipp
Götz, Thomas
Krueger, Tyll
Niedzielewski, Karol
Priesemann, Viola
Schaefer, Moritz
contents Households play an important role in disease dynamics. Many infections happening there due to the close contact, while mitigation measures mainly target the transmission between households. Therefore, one can see households as boosting the transmission depending on household size. To study the effect of household size and size distribution, we differentiated the within and between household reproduction rate. There are basically no preventive measures, and thus the close contacts can boost the spread. We explicitly incorporated that typically only a fraction of all household members are infected. Thus, viewing the infection of a household of a given size as a splitting process generating a new, small fully infected sub-household and a remaining still susceptible sub-household we derive a compartmental ODE-model for the dynamics of the sub-households. In this setting, the basic reproduction number as well as prevalence and the peak of an infection wave in a population with given households size distribution can be computed analytically. We compare numerical simulation results of this novel household-ODE model with results from an agent--based model using data for realistic household size distributions of different countries. We find good agreement of both models showing the catalytic effect of large households on the overall disease dynamics.
format Preprint
id arxiv_https___arxiv_org_abs_2301_04355
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle SIR-Model for Households
Doenges, Philipp
Götz, Thomas
Krueger, Tyll
Niedzielewski, Karol
Priesemann, Viola
Schaefer, Moritz
Populations and Evolution
92D30, 93-10
Households play an important role in disease dynamics. Many infections happening there due to the close contact, while mitigation measures mainly target the transmission between households. Therefore, one can see households as boosting the transmission depending on household size. To study the effect of household size and size distribution, we differentiated the within and between household reproduction rate. There are basically no preventive measures, and thus the close contacts can boost the spread. We explicitly incorporated that typically only a fraction of all household members are infected. Thus, viewing the infection of a household of a given size as a splitting process generating a new, small fully infected sub-household and a remaining still susceptible sub-household we derive a compartmental ODE-model for the dynamics of the sub-households. In this setting, the basic reproduction number as well as prevalence and the peak of an infection wave in a population with given households size distribution can be computed analytically. We compare numerical simulation results of this novel household-ODE model with results from an agent--based model using data for realistic household size distributions of different countries. We find good agreement of both models showing the catalytic effect of large households on the overall disease dynamics.
title SIR-Model for Households
topic Populations and Evolution
92D30, 93-10
url https://arxiv.org/abs/2301.04355