Unsupervised learning of representative local atomic arrangements in molecular dynamics data

Fuente: arXiv
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Autori principali: Roncoroni, Fabrice, Sanz-Matias, Ana, Sundararaman, Siddharth, Prendergast, David
Natura: Preprint
Pubblicazione: 2023
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author Roncoroni, Fabrice
Sanz-Matias, Ana
Sundararaman, Siddharth
Prendergast, David
author_facet Roncoroni, Fabrice
Sanz-Matias, Ana
Sundararaman, Siddharth
Prendergast, David
contents Molecular dynamics (MD) simulations present a data-mining challenge, given that they can generate a considerable amount of data but often rely on limited or biased human interpretation to examine their information content. By not asking the right questions of MD data we may miss critical information hidden within it. We combine dimensionality reduction (UMAP) and unsupervised hierarchical clustering (HDBSCAN) to quantitatively characterize prevalent coordination environments of chemical species within MD data. By focusing on local coordination, we significantly reduce the amount of data to be analyzed by extracting all distinct molecular formulas within a given coordination sphere. We then efficiently combine UMAP and HDBSCAN with alignment or shape-matching algorithms to partition these formulas into structural isomer families indicating their relative populations. The method was employed to reveal details of cation coordination in electrolytes based on molecular liquids.
format Preprint
id arxiv_https___arxiv_org_abs_2302_01465
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Unsupervised learning of representative local atomic arrangements in molecular dynamics data
Roncoroni, Fabrice
Sanz-Matias, Ana
Sundararaman, Siddharth
Prendergast, David
Materials Science
Chemical Physics
Computational Physics
Molecular dynamics (MD) simulations present a data-mining challenge, given that they can generate a considerable amount of data but often rely on limited or biased human interpretation to examine their information content. By not asking the right questions of MD data we may miss critical information hidden within it. We combine dimensionality reduction (UMAP) and unsupervised hierarchical clustering (HDBSCAN) to quantitatively characterize prevalent coordination environments of chemical species within MD data. By focusing on local coordination, we significantly reduce the amount of data to be analyzed by extracting all distinct molecular formulas within a given coordination sphere. We then efficiently combine UMAP and HDBSCAN with alignment or shape-matching algorithms to partition these formulas into structural isomer families indicating their relative populations. The method was employed to reveal details of cation coordination in electrolytes based on molecular liquids.
title Unsupervised learning of representative local atomic arrangements in molecular dynamics data
topic Materials Science
Chemical Physics
Computational Physics
url https://arxiv.org/abs/2302.01465