A distribution-free mixed-integer optimization approach to hierarchical modelling of clustered and longitudinal data

Fuente: arXiv
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Auteurs principaux: Sankaranarayanan, Madhav, Hossain, Intekhab, Chen, Tom
Format: Preprint
Publié: 2023
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author Sankaranarayanan, Madhav
Hossain, Intekhab
Chen, Tom
author_facet Sankaranarayanan, Madhav
Hossain, Intekhab
Chen, Tom
contents Recent advancements in Mixed Integer Optimization (MIO) algorithms, paired with hardware enhancements, have led to significant speedups in resolving MIO problems. These strategies have been utilized for optimal subset selection, specifically for choosing $k$ features out of $p$ in linear regression given $n$ observations. In this paper, we broaden this method to facilitate cluster-aware regression, where selection aims to choose $λ$ out of $K$ clusters in a linear mixed effects (LMM) model with $n_k$ observations for each cluster. Through comprehensive testing on a multitude of synthetic and real datasets, we exhibit that our method efficiently solves problems within minutes. Through numerical experiments, we also show that the MIO approach outperforms both Gaussian- and Laplace-distributed LMMs in terms of generating sparse solutions with high predictive power. Traditional LMMs typically assume that clustering effects are independent of individual features. However, we introduce an innovative algorithm that evaluates cluster effects for new data points, thereby increasing the robustness and precision of this model. The inferential and predictive efficacy of this approach is further illustrated through its application in student scoring and protein expression.
format Preprint
id arxiv_https___arxiv_org_abs_2302_03157
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle A distribution-free mixed-integer optimization approach to hierarchical modelling of clustered and longitudinal data
Sankaranarayanan, Madhav
Hossain, Intekhab
Chen, Tom
Methodology
Optimization and Control
Machine Learning
Recent advancements in Mixed Integer Optimization (MIO) algorithms, paired with hardware enhancements, have led to significant speedups in resolving MIO problems. These strategies have been utilized for optimal subset selection, specifically for choosing $k$ features out of $p$ in linear regression given $n$ observations. In this paper, we broaden this method to facilitate cluster-aware regression, where selection aims to choose $λ$ out of $K$ clusters in a linear mixed effects (LMM) model with $n_k$ observations for each cluster. Through comprehensive testing on a multitude of synthetic and real datasets, we exhibit that our method efficiently solves problems within minutes. Through numerical experiments, we also show that the MIO approach outperforms both Gaussian- and Laplace-distributed LMMs in terms of generating sparse solutions with high predictive power. Traditional LMMs typically assume that clustering effects are independent of individual features. However, we introduce an innovative algorithm that evaluates cluster effects for new data points, thereby increasing the robustness and precision of this model. The inferential and predictive efficacy of this approach is further illustrated through its application in student scoring and protein expression.
title A distribution-free mixed-integer optimization approach to hierarchical modelling of clustered and longitudinal data
topic Methodology
Optimization and Control
Machine Learning
url https://arxiv.org/abs/2302.03157