Universal bounds on optimization of free energy harvesting

Fuente: arXiv
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Hauptverfasser: Piñero, Jordi, Solé, Ricard, Kolchinsky, Artemy
Format: Preprint
Veröffentlicht: 2023
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author Piñero, Jordi
Solé, Ricard
Kolchinsky, Artemy
author_facet Piñero, Jordi
Solé, Ricard
Kolchinsky, Artemy
contents Harvesting free energy from the environment is essential for the operation of many biological and artificial systems. We investigate the maximum rate of harvesting achievable by optimizing a set of reactions in a Markovian system, possibly given topological, kinetic, and thermodynamic constraints. We show that the maximum harvesting rate can be expressed as a variational principle, which we solve in closed-form for three physically meaningful regimes. Our approach is relevant for optimal design and for quantifying efficiency of existing reactions. Our results are illustrated on bacteriorhodopsin, a light-driven proton pump from Archae, which is found to be close to optimal under realistic conditions.
format Preprint
id arxiv_https___arxiv_org_abs_2303_04975
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Universal bounds on optimization of free energy harvesting
Piñero, Jordi
Solé, Ricard
Kolchinsky, Artemy
Statistical Mechanics
Adaptation and Self-Organizing Systems
Biological Physics
Harvesting free energy from the environment is essential for the operation of many biological and artificial systems. We investigate the maximum rate of harvesting achievable by optimizing a set of reactions in a Markovian system, possibly given topological, kinetic, and thermodynamic constraints. We show that the maximum harvesting rate can be expressed as a variational principle, which we solve in closed-form for three physically meaningful regimes. Our approach is relevant for optimal design and for quantifying efficiency of existing reactions. Our results are illustrated on bacteriorhodopsin, a light-driven proton pump from Archae, which is found to be close to optimal under realistic conditions.
title Universal bounds on optimization of free energy harvesting
topic Statistical Mechanics
Adaptation and Self-Organizing Systems
Biological Physics
url https://arxiv.org/abs/2303.04975