Using AI to Measure Parkinson's Disease Severity at Home

Fuente: arXiv
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Auteurs principaux: Islam, Md Saiful, Rahman, Wasifur, Abdelkader, Abdelrahman, Yang, Phillip T., Lee, Sangwu, Adams, Jamie L., Schneider, Ruth B., Dorsey, E. Ray, Hoque, Ehsan
Format: Preprint
Publié: 2023
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author Islam, Md Saiful
Rahman, Wasifur
Abdelkader, Abdelrahman
Yang, Phillip T.
Lee, Sangwu
Adams, Jamie L.
Schneider, Ruth B.
Dorsey, E. Ray
Hoque, Ehsan
author_facet Islam, Md Saiful
Rahman, Wasifur
Abdelkader, Abdelrahman
Yang, Phillip T.
Lee, Sangwu
Adams, Jamie L.
Schneider, Ruth B.
Dorsey, E. Ray
Hoque, Ehsan
contents We present an artificial intelligence system to remotely assess the motor performance of individuals with Parkinson's disease (PD). Participants performed a motor task (i.e., tapping fingers) in front of a webcam, and data from 250 global participants were rated by three expert neurologists following the Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS). The neurologists' ratings were highly reliable, with an intra-class correlation coefficient (ICC) of 0.88. We developed computer algorithms to obtain objective measurements that align with the MDS-UPDRS guideline and are strongly correlated with the neurologists' ratings. Our machine learning model trained on these measures outperformed an MDS-UPDRS certified rater, with a mean absolute error (MAE) of 0.59 compared to the rater's MAE of 0.79. However, the model performed slightly worse than the expert neurologists (0.53 MAE). The methodology can be replicated for similar motor tasks, providing the possibility of evaluating individuals with PD and other movement disorders remotely, objectively, and in areas with limited access to neurological care.
format Preprint
id arxiv_https___arxiv_org_abs_2303_17573
institution arXiv
publishDate 2023
record_format arxiv
spellingShingle Using AI to Measure Parkinson's Disease Severity at Home
Islam, Md Saiful
Rahman, Wasifur
Abdelkader, Abdelrahman
Yang, Phillip T.
Lee, Sangwu
Adams, Jamie L.
Schneider, Ruth B.
Dorsey, E. Ray
Hoque, Ehsan
Machine Learning
Artificial Intelligence
We present an artificial intelligence system to remotely assess the motor performance of individuals with Parkinson's disease (PD). Participants performed a motor task (i.e., tapping fingers) in front of a webcam, and data from 250 global participants were rated by three expert neurologists following the Movement Disorder Society Unified Parkinson's Disease Rating Scale (MDS-UPDRS). The neurologists' ratings were highly reliable, with an intra-class correlation coefficient (ICC) of 0.88. We developed computer algorithms to obtain objective measurements that align with the MDS-UPDRS guideline and are strongly correlated with the neurologists' ratings. Our machine learning model trained on these measures outperformed an MDS-UPDRS certified rater, with a mean absolute error (MAE) of 0.59 compared to the rater's MAE of 0.79. However, the model performed slightly worse than the expert neurologists (0.53 MAE). The methodology can be replicated for similar motor tasks, providing the possibility of evaluating individuals with PD and other movement disorders remotely, objectively, and in areas with limited access to neurological care.
title Using AI to Measure Parkinson's Disease Severity at Home
topic Machine Learning
Artificial Intelligence
url https://arxiv.org/abs/2303.17573