A comparison of 7 Tesla MR spectroscopic imaging and 3 Tesla MR fingerprinting for tumor localization in glioma patients
Fuente:
arXiv
Enregistré dans:
| Auteurs principaux: | , , , , , , , , , , , , , , , |
|---|---|
| Format: | Preprint |
| Publié: |
2023
|
| Sujets: | |
| Accès en ligne: | |
| Tags: |
Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!
|
| _version_ | 1866916136468086784 |
|---|---|
| author | Lazen, Philipp Cardoso, Pedro Lima Sharma, Sukrit Cadrien, Cornelius Roetzer-Pejrimovsky, Thomas Furtner, Julia Strasser, Bernhard Hingerl, Lukas Lipka, Alexandra Preusser, Matthias Marik, Wolfgang Bogner, Wolfgang Widhalm, Georg Rössler, Karl Trattnig, Siegfried Hangel, Gilbert |
| author_facet | Lazen, Philipp Cardoso, Pedro Lima Sharma, Sukrit Cadrien, Cornelius Roetzer-Pejrimovsky, Thomas Furtner, Julia Strasser, Bernhard Hingerl, Lukas Lipka, Alexandra Preusser, Matthias Marik, Wolfgang Bogner, Wolfgang Widhalm, Georg Rössler, Karl Trattnig, Siegfried Hangel, Gilbert |
| contents | This paper investigates the correlation between magnetic resonance spectroscopic imaging (MRSI) and magnetic resonance fingerprinting (MRF) in glioma patients by comparing neuro-oncological markers obtained from MRSI to T1/T2 maps from MRF.
Data from 12 consenting patients with gliomas were analyzed by defining hotspots for T1, T2 and various metabolic ratios, and comparing them using Sørensen-Dice Similarity Coefficients (DSCs) and the distances between their centers of intensity (COIDs).
Median DSCs between MRF and the tumor segmentation were 0.73 (T1) and 0.79 (T2). The DSCs between MRSI and MRF were highest for Gln/tNAA (T1: 0.75, T2: 0.80, tumor: 0.78), followed by Gly/tNAA (T1: 0.57, T2: 0.62, tumor: 0.54) and tCho/tNAA (T1: 0.61, T2: 0.58, tumor: 0.45). The median values in the tumor hotspot were T1=1724 ms, T2=86 ms, Gln/tNAA=0.61, Gly/tNAA=0.28, Ins/tNAA=1.15, and tCho/tNAA=0.48, and, in the peritumoral region, were T1=1756 ms, T2=102ms, Gln/tNAA=0.38, Gly/tNAA=0.20, Ins/tNAA=1.06, and tCho/tNAA=0.38, and, in the NAWM, were T1=950 ms, T2=43 ms, Gln/tNAA=0.16, Gly/tNAA=0.07, Ins/tNAA=0.54, and tCho/tNAA=0.20.
The results of this study constitute the first comparison of 7T MRSI and 3T MRF, showing a good correspondence between these methods. |
| format | Preprint |
| id |
arxiv_https___arxiv_org_abs_2304_05254 |
| institution | arXiv |
| publishDate | 2023 |
| record_format | arxiv |
| spellingShingle | A comparison of 7 Tesla MR spectroscopic imaging and 3 Tesla MR fingerprinting for tumor localization in glioma patients Lazen, Philipp Cardoso, Pedro Lima Sharma, Sukrit Cadrien, Cornelius Roetzer-Pejrimovsky, Thomas Furtner, Julia Strasser, Bernhard Hingerl, Lukas Lipka, Alexandra Preusser, Matthias Marik, Wolfgang Bogner, Wolfgang Widhalm, Georg Rössler, Karl Trattnig, Siegfried Hangel, Gilbert Medical Physics This paper investigates the correlation between magnetic resonance spectroscopic imaging (MRSI) and magnetic resonance fingerprinting (MRF) in glioma patients by comparing neuro-oncological markers obtained from MRSI to T1/T2 maps from MRF. Data from 12 consenting patients with gliomas were analyzed by defining hotspots for T1, T2 and various metabolic ratios, and comparing them using Sørensen-Dice Similarity Coefficients (DSCs) and the distances between their centers of intensity (COIDs). Median DSCs between MRF and the tumor segmentation were 0.73 (T1) and 0.79 (T2). The DSCs between MRSI and MRF were highest for Gln/tNAA (T1: 0.75, T2: 0.80, tumor: 0.78), followed by Gly/tNAA (T1: 0.57, T2: 0.62, tumor: 0.54) and tCho/tNAA (T1: 0.61, T2: 0.58, tumor: 0.45). The median values in the tumor hotspot were T1=1724 ms, T2=86 ms, Gln/tNAA=0.61, Gly/tNAA=0.28, Ins/tNAA=1.15, and tCho/tNAA=0.48, and, in the peritumoral region, were T1=1756 ms, T2=102ms, Gln/tNAA=0.38, Gly/tNAA=0.20, Ins/tNAA=1.06, and tCho/tNAA=0.38, and, in the NAWM, were T1=950 ms, T2=43 ms, Gln/tNAA=0.16, Gly/tNAA=0.07, Ins/tNAA=0.54, and tCho/tNAA=0.20. The results of this study constitute the first comparison of 7T MRSI and 3T MRF, showing a good correspondence between these methods. |
| title | A comparison of 7 Tesla MR spectroscopic imaging and 3 Tesla MR fingerprinting for tumor localization in glioma patients |
| topic | Medical Physics |
| url | https://arxiv.org/abs/2304.05254 |